Cardiac Electrophysiological Changes and Downregulated Connexin 43 Prompts Reperfusion Arrhythmias Induced by Hypothermic Ischemia–Reperfusion Injury in Isolated Rat Hearts

The purpose of this study was to determine the utility of the monophasic action potential (MAP) changes as an arrhythmic biomarker in hypothermic ischemia–reperfusion. The hypothermic ischemia–reperfusion model was subjected to 60 min of cardioplegic arrest while the isolated rat hearts were preserv...

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Veröffentlicht in:	Journal of cardiovascular translational research 2022-12, Vol.15 (6), p.1464-1473
Hauptverfasser:	Yi, Jing, Duan, Hongwei, Chen, Kaiyuan, Wen, Chunlei, Cao, Ying, Gao, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - metabolism Biomarkers - metabolism Biomedical Engineering and Bioengineering Biomedicine Cardiology Connexin 43 - metabolism Human Genetics Medicine Medicine & Public Health Myocardium - metabolism Original Article Rats Reperfusion Reperfusion Injury - metabolism
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