The truncated MyD88s negatively regulates TLR2 signal on expression of IL17-1 in oyster Crassostrea gigas

Toll like receptor (TLR) signaling plays a key role in the innate immune recognition and inflammatory regulation in both vertebrates and invertebrates. The expanded TLR signaling components, including 83 TLRs and 10 MyD88s, have been reported in the genome of the Pacific oyster Crassostrea gigas. In...

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Veröffentlicht in:	Developmental and comparative immunology 2022-08, Vol.133, p.104446-104446, Article 104446
Hauptverfasser:	Fan, Siqi, Wang, Weilin, Li, Jialuo, Cao, Wanqing, Li, Qing, Wu, Shasha, Wang, Lingling, Song, Linsheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Crassostrea gigas Down-regulation Gene expression genome Genomes granulocytes Hemocytes IL17-1 Immune regulation Immune response Immune system Inflammation Interleukin 1 Interleukin 17 Invertebrates Leukocytes (granulocytic) Lipopolysaccharides MyD88 Oysters Proteins recombinant proteins Signaling siRNA Stimulation TLR signal TLR2 protein Toll-like receptors Vertebrates Vibrio splendidus
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