Heavy Chain Constant Region Usage in Antibodies to Peptidylarginine Deiminase 4 as a Marker of Disease Subsets in Rheumatoid Arthritis

Objective The study of autoantibody isotypes in autoimmune diseases is useful for identifying clinically relevant endotypes. This study was undertaken to study the prevalence and clinical significance of different isotypes and IgG subclasses of anti–peptidylarginine deiminase 4 (anti‐PAD4) autoantib...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2022-11, Vol.74 (11), p.1746-1754
Hauptverfasser:	Gómez‐Bañuelos, E., Shi, J., Wang, H., Danila, M. I., Bridges, S. L., Giles, J. T., Sims, G. P., Andrade, F., Darrah, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Arthritis Autoantibodies Autoimmune diseases Chains Citrulline Constant region Damage Disease Immunoglobulin A Immunoglobulin E Immunoglobulin G Interleukin 6 Interleukins Isotypes Joint diseases Joints (anatomy) Lung diseases Nodules Patients Protein-arginine deiminase Rheumatoid arthritis Rheumatoid factor
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