Site-Specific 19F NMR Method for Detecting Arf6 GEF Activity

Guanine nucleotide exchange factors (GEFs) of small GTPase (sGTPase) coordinate signal networks in normal cells and dysfunction in cancer. Therefore, effective monitoring of GEF activity is very important for studying the regulation of sGTPase signal transduction. In this study, we developed a 1D 19...

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Veröffentlicht in:	Analytical chemistry (Washington) 2022-06, Vol.94 (23), p.8181-8186
Hauptverfasser:	Wang, Jiarong, Wu, Bo, Zhang, Youjia, Ge, Liang, Wang, Junfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Guanine Guanine nucleotide exchange factor NMR Nuclear magnetic resonance Nucleotides Regulatory proteins Signal transduction
Online-Zugang:	Volltext
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