Sweet's syndrome and Crohn's disease diagnosed simultaneously
Additionally, in his medical history, he had type 2 diabetes, arterial hypertension, and dyslipidaemia: he was prescribed metformin, gliclazide, enalapril, a thiazide diuretic, and simvastatin. Laboratory investigations showed a haemoglobin concentration of 7·6 g/dL (normal 13·0–16·5), white blood c...
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| Veröffentlicht in: | The Lancet (British edition) 2022-06, Vol.399 (10341), p.2155-2155 |
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| creator | Bañares, Juan Aceituno, Laia Jiménez, Alba Maynard, Avonello Escobar, Eduardo Dacosta Alemán, Carmen |
| description | Additionally, in his medical history, he had type 2 diabetes, arterial hypertension, and dyslipidaemia: he was prescribed metformin, gliclazide, enalapril, a thiazide diuretic, and simvastatin. Laboratory investigations showed a haemoglobin concentration of 7·6 g/dL (normal 13·0–16·5), white blood cell count of 7·6 × 109 per L (normal 4·5–11·0), neutrophil count of 6·0 × 109 per L (normal 2·0–7·0), and elevated acute phase reactants: ferritin concentration was 533 ng/mL (normal 25–400), erythrocyte sedimentation rate was 120 mm/h (normal 1–10), and C-reactive protein concentration was 15 mg/dL (normal |
| doi_str_mv | 10.1016/S0140-6736(22)00915-1 |
| format | Article |
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Laboratory investigations showed a haemoglobin concentration of 7·6 g/dL (normal 13·0–16·5), white blood cell count of 7·6 × 109 per L (normal 4·5–11·0), neutrophil count of 6·0 × 109 per L (normal 2·0–7·0), and elevated acute phase reactants: ferritin concentration was 533 ng/mL (normal 25–400), erythrocyte sedimentation rate was 120 mm/h (normal 1–10), and C-reactive protein concentration was 15 mg/dL (normal <5). At colonoscopy we found multiple star-shaped ulcers scattered throughout the colon with areas of preserved mucosa between them (figure); histological analysis showed active chronic colitis with crypt inflammatory destruction and abscesses.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(22)00915-1</identifier><identifier>PMID: 35658996</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Abscesses ; Biopsy ; C-reactive protein ; Colitis ; Colon ; Colonoscopy ; Crohn Disease - complications ; Crohn Disease - diagnosis ; Crohn's disease ; Diabetes mellitus (non-insulin dependent) ; Diuretics ; Dyslipidemia ; Erythrocyte sedimentation rate ; Erythrocytes ; Ferritin ; Fever ; Fistula ; Hemoglobin ; Humans ; Hypertension ; Inflammation ; Inflammatory bowel diseases ; Leukocytes ; Leukocytes (neutrophilic) ; Medical diagnosis ; Metabolic disorders ; Metformin ; Simvastatin ; Sweet Syndrome - diagnosis ; Sweet's syndrome ; Ulcers</subject><ispartof>The Lancet (British edition), 2022-06, Vol.399 (10341), p.2155-2155</ispartof><rights>2022 Elsevier Ltd</rights><rights>2022. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-d3ed7fda4d015ba254565428a5d8566e851b9fd97dc46d3b393b6cf8b702efa83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2672672947?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72341</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35658996$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bañares, Juan</creatorcontrib><creatorcontrib>Aceituno, Laia</creatorcontrib><creatorcontrib>Jiménez, Alba</creatorcontrib><creatorcontrib>Maynard, Avonello</creatorcontrib><creatorcontrib>Escobar, Eduardo Dacosta</creatorcontrib><creatorcontrib>Alemán, Carmen</creatorcontrib><title>Sweet's syndrome and Crohn's disease diagnosed simultaneously</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>Additionally, in his medical history, he had type 2 diabetes, arterial hypertension, and dyslipidaemia: he was prescribed metformin, gliclazide, enalapril, a thiazide diuretic, and simvastatin. Laboratory investigations showed a haemoglobin concentration of 7·6 g/dL (normal 13·0–16·5), white blood cell count of 7·6 × 109 per L (normal 4·5–11·0), neutrophil count of 6·0 × 109 per L (normal 2·0–7·0), and elevated acute phase reactants: ferritin concentration was 533 ng/mL (normal 25–400), erythrocyte sedimentation rate was 120 mm/h (normal 1–10), and C-reactive protein concentration was 15 mg/dL (normal <5). At colonoscopy we found multiple star-shaped ulcers scattered throughout the colon with areas of preserved mucosa between them (figure); histological analysis showed active chronic colitis with crypt inflammatory destruction and abscesses.</description><subject>Abscesses</subject><subject>Biopsy</subject><subject>C-reactive protein</subject><subject>Colitis</subject><subject>Colon</subject><subject>Colonoscopy</subject><subject>Crohn Disease - complications</subject><subject>Crohn Disease - diagnosis</subject><subject>Crohn's disease</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diuretics</subject><subject>Dyslipidemia</subject><subject>Erythrocyte sedimentation rate</subject><subject>Erythrocytes</subject><subject>Ferritin</subject><subject>Fever</subject><subject>Fistula</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Inflammation</subject><subject>Inflammatory bowel 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hypertension, and dyslipidaemia: he was prescribed metformin, gliclazide, enalapril, a thiazide diuretic, and simvastatin. 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| subjects | Abscesses Biopsy C-reactive protein Colitis Colon Colonoscopy Crohn Disease - complications Crohn Disease - diagnosis Crohn's disease Diabetes mellitus (non-insulin dependent) Diuretics Dyslipidemia Erythrocyte sedimentation rate Erythrocytes Ferritin Fever Fistula Hemoglobin Humans Hypertension Inflammation Inflammatory bowel diseases Leukocytes Leukocytes (neutrophilic) Medical diagnosis Metabolic disorders Metformin Simvastatin Sweet Syndrome - diagnosis Sweet's syndrome Ulcers |
| title | Sweet's syndrome and Crohn's disease diagnosed simultaneously |
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