Di-(2-ethyl hexyl) phthalate induced oxidative stress promotes microplastics mediated apoptosis and necroptosis in mice skeletal muscle by inhibiting PI3K/AKT/mTOR pathway

The plastic decomposition product microplastics (MPs) and the plastic additive Di (2-ethylhexyl) phthalate (DEHP) in the environment can damage various organs of the organism by inducing oxidative stress. The PI3K/AKT/mTOR signaling pathway participate in toxin-induced apoptosis and necroptosis. How...

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Veröffentlicht in:Toxicology (Amsterdam) 2022-05, Vol.474, p.153226-153226, Article 153226
Hauptverfasser: Liu, Xiaojing, Zhang, Yilei, Sun, Xinyue, Zhang, Wenyue, Shi, Xu, Xu, Shiwen
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Sprache:eng
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