Synthetic negative genome screen of the GPN-loop GTPase NPA3 in Saccharomyces cerevisiae

The GPN-loop GTPase Npa3 is encoded by an essential gene in the yeast Saccharomyces cerevisiae . Npa3 plays a critical role in the assembly and nuclear accumulation of RNA polymerase II (RNAPII), a function that may explain its essentiality. Genetic interactions describe the extent to which a mutati...

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Veröffentlicht in:	Current genetics 2022-08, Vol.68 (3-4), p.343-360
Hauptverfasser:	Mora-García, Martín, Ascencio, Diana, Félix-Pérez, Tania, Ulloa-Calzonzin, Judith, Juárez-Reyes, Alejandro, Robledo-Márquez, Karina, Rebolloso-Gómez, Yolanda, Riego-Ruiz, Lina, DeLuna, Alexander, Calera, Mónica R., Sánchez-Olea, Roberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Archaea Biochemistry Biological activity Biomedical and Life Sciences Cell Biology DNA-directed RNA polymerase Eukaryotes Evolution Gene deletion Genes Genetic screening Genomes Guanosine triphosphatases Homeostasis Life Sciences Microbial Genetics and Genomics Microbiology Mitochondria Mutation Original Article Phenotypes Plant Sciences Proteomics RNA polymerase RNA polymerase II Saccharomyces cerevisiae Yeast Yeasts
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