Drug metabolic enzyme genotype-phenotype discrepancy: High phenoconversion rate in patients treated with antidepressants

Cytochromes from the P450 family (CYP) play a central role in the primary metabolism of frequently prescribed antidepressants, potentially affecting their efficacy and tolerance. There are however important differences in the drug metabolic capacities of each individual resulting from a combination...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2022-08, Vol.152, p.113202-113202, Article 113202
Hauptverfasser:	Gloor, Y., Lloret-Linares, C., Bosilkovska, M., Perroud, N., Richard-Lepouriel, H., Aubry, J.-M., Daali, Y., Desmeules, J.A., Besson, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressant treatment Cytochrome P450 Genotype Phenoconversion Phenotype
Online-Zugang:	Volltext
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