Inflammatory leiomyosarcoma/rhabdomyoblastic tumor: A report of two cases with novel genetic findings

Inflammatory leiomyosarcoma (ILMS) is a malignant neoplasm showing smooth muscle differentiation, a prominent inflammatory infiltrate, and near‐haploidization. These tumors have significant pathologic and genetic overlap with the recently described “inflammatory rhabdomyoblastic tumor (IRT),” sugges...

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Veröffentlicht in:	Genes chromosomes & cancer 2022-11, Vol.61 (11), p.653-661
Hauptverfasser:	Sukhanova, Madina, Obeidin, Farres, Streich, Lukas, Alexiev, Borislav A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes Colorectal cancer Colorectal carcinoma Copy number Cytogenetics Cytology Diploids driver mutations Genetic disorders Genetic transformation Heterozygosity Inflammation inflammatory leiomyosarcoma/rhabdomyoblastic tumor inflammatory rhabdomyoblastic tumor Loss of heterozygosity MSH6 protein p53 Protein Smooth muscle Tumor cells Tumors
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