Interactions Among Brain-Derived Neurotrophic Factor and Neuroimmune Pathways Are Key Components of the Major Psychiatric Disorders

The purpose of this review is to summarize the current knowledge regarding the reciprocal associations between brain-derived neurotrophic factor (BDNF) and immune-inflammatory pathways and how these links may explain the involvement of this neurotrophin in the immune pathophysiology of mood disorder...

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Veröffentlicht in:	Molecular neurobiology 2022-08, Vol.59 (8), p.4926-4952
Hauptverfasser:	Mehterov, Nikolay, Minchev, Danail, Gevezova, Maria, Sarafian, Victoria, Maes, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Brain-derived neurotrophic factor Cell adhesion Cell Biology Cytokines Disc1 protein E-cadherin Emotional disorders Homology Immune response Inflammation Mental disorders Mood Mood disorders Nerve growth factor receptors Neurobiology Neurology Neuroprotection Neurosciences Neurotoxicity Protein-tyrosine kinase receptors Protein-tyrosine-phosphatase Psychosis Schizophrenia Signal transduction Stat3 protein Synapses TRAF6 protein
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