Subacute and sublethal ingestion of microcystin-LR impairs lung mitochondrial function by an oligomycin-like effect

Microcystin-LR (MC-LR) is a potent cyanotoxin that can reach several organs. However subacute exposure to sublethal doses of MC-LR has not yet well been studied. Herein, we evaluated the outcomes of subacute and sublethal MC-LR exposure on lungs. Male BALB/c mice were exposed to MC-LR by gavage (30 ...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2022-07, Vol.93, p.103887-103887, Article 103887
Hauptverfasser:	Mesquita, Flávia Muniz de, de Oliveira, Dahienne Ferreira, Caldeira, Dayene de Assis Fernandes, de Albuquerque, João Paulo Cavalcante, Matta, Leonardo, Faria, Caroline Coelho de, Souza, Itanna Isis Araujo de, Takiya, Christina Maeda, Fortunato, Rodrigo Soares, Nascimento, José Hamilton Matheus, de Oliveira Azevedo, Sandra Maria Feliciano, Zin, Walter Araujo, Maciel, Leonardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Collagen Exposure Histology Histopathology Immunology Ingestion Intoxication Lung Lungs Microcystin-LR Mitochondria Mitochondrial function Oligomycin Organs Subacute exposure Titration Water purification
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