Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry
Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the analysis process, sample preparation and instrume...
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Veröffentlicht in: | Mass spectrometry reviews 2023-09, Vol.42 (5), p.1808-1827 |
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description | Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the analysis process, sample preparation and instrument analysis are key steps to improve analysis performance and accuracy. In recent years, chromatography combined with mass spectrometry (MS) has been widely used for the separation and detection of trace components in complex TCM samples. This article reviews various sample preparation techniques and chromatography‐MS techniques, including the application of gas chromatography‐MS and liquid chromatography‐MS and other MS techniques in the characterization of phytochemicals in TCM materials and Chinese medicine products. This article also describes a new ambient ionization MS method for rapid and high‐throughput analysis of TCM components. |
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This article also describes a new ambient ionization MS method for rapid and high‐throughput analysis of TCM components.</description><identifier>ISSN: 0277-7037</identifier><identifier>EISSN: 1098-2787</identifier><identifier>DOI: 10.1002/mas.21782</identifier><identifier>PMID: 35638257</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>ambient ionization ; chromatography ; Gas chromatography ; Ionization ; Liquid chromatography ; mass spectrometry ; Mass spectroscopy ; Phytochemicals ; sample extraction technique ; Traditional Chinese medicine</subject><ispartof>Mass spectrometry reviews, 2023-09, Vol.42 (5), p.1808-1827</ispartof><rights>2022 John Wiley & Sons Ltd.</rights><rights>2023 John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3532-547ba3a3295301725f309826f8d9141eac98585ac47c6e985ebfef5f5fa37f293</citedby><cites>FETCH-LOGICAL-c3532-547ba3a3295301725f309826f8d9141eac98585ac47c6e985ebfef5f5fa37f293</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmas.21782$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmas.21782$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27931,27932,45581,45582</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35638257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Chung‐Yu</creatorcontrib><creatorcontrib>Li, Yen‐Hsien</creatorcontrib><creatorcontrib>Li, Zuguang</creatorcontrib><creatorcontrib>Lee, Maw‐Rong</creatorcontrib><title>Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry</title><title>Mass spectrometry reviews</title><addtitle>Mass Spectrom Rev</addtitle><description>Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the analysis process, sample preparation and instrument analysis are key steps to improve analysis performance and accuracy. In recent years, chromatography combined with mass spectrometry (MS) has been widely used for the separation and detection of trace components in complex TCM samples. This article reviews various sample preparation techniques and chromatography‐MS techniques, including the application of gas chromatography‐MS and liquid chromatography‐MS and other MS techniques in the characterization of phytochemicals in TCM materials and Chinese medicine products. This article also describes a new ambient ionization MS method for rapid and high‐throughput analysis of TCM components.</description><subject>ambient ionization</subject><subject>chromatography</subject><subject>Gas chromatography</subject><subject>Ionization</subject><subject>Liquid chromatography</subject><subject>mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Phytochemicals</subject><subject>sample extraction technique</subject><subject>Traditional Chinese medicine</subject><issn>0277-7037</issn><issn>1098-2787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kD1PwzAQhi0EoqUw8AeQJRYY0vojjpOxiviSihiA2XLds-oqaYqdgMKvx6WFAQndcDc89969L0LnlIwpIWxS6zBmVObsAA0pKfKEyVweoiFhUiaScDlAJyGsCKFUUHqMBlxkPGdCDpEul9pr04J3n7p1zRo3FoO1YFr3Dniz7NvGLKF2RlcBuzVuvV64LagrXC7dGgLgGhbOxBHPexx_CThs4r5vamh9f4qObNyFs30fodfbm5fyPpk93T2U01liuOAsEamca645KwQnVDJheXTCMpsvCppS0KbIRS60SaXJIM4wt2BFLM2lZQUfoaud7sY3bx2EVtUuGKgqvYamC4plknEm05RF9PIPumo6Hx1FKk8lzeJFEqnrHWV8E4IHqzbe1dr3ihK1zV1Fr-o798he7BW7eUzjl_wJOgKTHfDhKuj_V1KP0-ed5BeM8ozV</recordid><startdate>202309</startdate><enddate>202309</enddate><creator>Chen, Chung‐Yu</creator><creator>Li, Yen‐Hsien</creator><creator>Li, Zuguang</creator><creator>Lee, Maw‐Rong</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>202309</creationdate><title>Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry</title><author>Chen, Chung‐Yu ; Li, Yen‐Hsien ; Li, Zuguang ; Lee, Maw‐Rong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3532-547ba3a3295301725f309826f8d9141eac98585ac47c6e985ebfef5f5fa37f293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>ambient ionization</topic><topic>chromatography</topic><topic>Gas chromatography</topic><topic>Ionization</topic><topic>Liquid chromatography</topic><topic>mass spectrometry</topic><topic>Mass spectroscopy</topic><topic>Phytochemicals</topic><topic>sample extraction technique</topic><topic>Traditional Chinese medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Chung‐Yu</creatorcontrib><creatorcontrib>Li, Yen‐Hsien</creatorcontrib><creatorcontrib>Li, Zuguang</creatorcontrib><creatorcontrib>Lee, Maw‐Rong</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Mass spectrometry reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Chung‐Yu</au><au>Li, Yen‐Hsien</au><au>Li, Zuguang</au><au>Lee, Maw‐Rong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry</atitle><jtitle>Mass spectrometry reviews</jtitle><addtitle>Mass Spectrom Rev</addtitle><date>2023-09</date><risdate>2023</risdate><volume>42</volume><issue>5</issue><spage>1808</spage><epage>1827</epage><pages>1808-1827</pages><issn>0277-7037</issn><eissn>1098-2787</eissn><abstract>Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. 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subjects | ambient ionization chromatography Gas chromatography Ionization Liquid chromatography mass spectrometry Mass spectroscopy Phytochemicals sample extraction technique Traditional Chinese medicine |
title | Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry |
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