Using American Type Culture Collection Cell Lines to Evaluate Interlaboratory Variables for Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Immunostaining

Most laboratories currently use patient tissues for validating immunohistochemical stains. To explore advantages of using cell lines with known antigenicity as a validation method. Five American Type Culture Collection (ATCC) cell lines with known negative, low positive, and moderate to strong estro...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2023-02, Vol.147 (2), p.143-148
Hauptverfasser:	Witt, Benjamin L, Zhou, Wenhua, Ambaye, Abiy B, Bellizzi, Andrew, Booth, Christine N, Sundling, Kaitlin, Nguyen, Lananh, Russell, Donna K, Schinstine, Malcolm, Staats, Paul N, Thomsen, Jean, Troxell, Megan, Souers, Rhona J, Dvorak, James, Lin, Xiaoqi, Kurtycz, Daniel F I
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor Breast Neoplasms Cell culture Cell lines Estrogen Female Humans Immunohistochemistry Methods Pathology, Cellular Receptor, ErbB-2 - metabolism Receptors Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Staining and Labeling
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