Molecular details of aluminium-amyloid β peptide interaction by nuclear magnetic resonance

Alzheimer’s disease (AD) is a devastating neurodegenerative condition that poses major challenges to human health. Both amyloid β (Aβ) and metal ions such as aluminium are implicated in the development of AD. By the means of NMR, the interactions of Al 3+ with Aβ 1–28 peptide as well as the Aβ 1–28...

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Veröffentlicht in:Biometals 2022-08, Vol.35 (4), p.759-769
Hauptverfasser: Petersingham, Gayani, Zaman, Mohammad S., Johnson, Adam J., Reddy, Narsimha, Torres, Allan M., Wu, Ming J.
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Sprache:eng
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