Quantitative imaging of natural products in fine brain regions using desorption electrospray ionization mass spectrometry imaging (DESI-MSI): Uncaria alkaloids as a case study

Uncaria species (Rubiaceae) are used as traditional Chinese medicines (TCMs) to treat central nervous system (CNS) diseases, and monoterpene indole alkaloids are the main bioactive constituents. Localization and quantification of CNS drugs in fine brain regions are important to provide insights into...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2022-07, Vol.414 (17), p.4999-5007
Hauptverfasser:	Gao, Lei, Zhang, Zijia, Wu, Wenyong, Deng, Yanping, Zhi, Haijuan, Long, Huali, Lei, Min, Hou, Jinjun, Wu, Wanying, Guo, De-an
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids Analytical Chemistry Biochemistry Brain Care and treatment Central nervous system Central nervous system diseases Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Configurations Desorption Electrospraying Food Science Health aspects Herbal medicine Ionization Ions Laboratory Medicine Localization Mass spectrometry Mass spectroscopy Measurement Medical imaging Medicinal plants Monitoring/Environmental Analysis Natural products Neuroimaging Oxindole alkaloids Pharmacodynamics Pharmacology Physiological aspects Pineal gland Research Paper Rubiaceae Scientific imaging Spectroscopy Traditional Chinese medicine Uncaria
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