MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1

To investigate the role and mechanism of microRNAs (miRNAs) in fibrotic processes involved in the pathology of systemic sclerosis (SSc). R language and bioinformatics methods were used to identify differential miRNAs and mRNAs and analyze their biological functions. Transfection experiments were per...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 2022-07, Vol.114 (4), p.110391-110391, Article 110391
Hauptverfasser:	Cheng, Qi, Chen, Mo, Wang, Huyan, Chen, Xin, Wu, Huaxiang, Du, Yan, Xue, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Lung miR-27a-3p Regulatory mechanism Skin SPP1 Systemic sclerosis Tissue fibrosis
Online-Zugang:	Volltext
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