Quercetin protects against palmitate-induced pancreatic β-cell apoptosis by restoring lysosomal function and autophagic flux

Quercetin, a natural flavonoid, has been reported to prevent pancreatic β-cell apoptosis in animal models of diabetes. However, the underlying mechanism remains unclear. We investigated the mechanisms through which quercetin protects β cells from palmitate-induced apoptosis and determined whether au...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2022-09, Vol.107, p.109060-109060, Article 109060
Hauptverfasser:	Liu, Hao, Zhou, Wenling, Guo, Lan, Zhang, Heng, Guan, Lingling, Yan, Xu, Zhai, Yuanyuan, Qiao, Yuan, Wang, Zai, Zhao, Junhua, Lyu, Kangbo, Li, Ping, Wang, Haitao, Peng, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagic flux Lysosomal dysfunction Quercetin β-cell apoptosis
Online-Zugang:	Volltext
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