Synergy between the Levels of Methylation of microRNA Gene Sets in Primary Tumors and Metastases of Ovarian Cancer Patients

We studied the correlations between the levels of methylation of a group of 21 microRNA genes in 99 primary tumors and 29 macroscopic peritoneal metastases of ovarian cancer. Analysis of the level of methylation by quantitative methylation-specific PCR showed that co-methylation was detected for 13...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2022-05, Vol.173 (1), p.87-91
Hauptverfasser:	Lukina, S. S., Burdennyy, A. M., Filippova, E. A., Pronina, I. V., Ivanova, N. A., Kazubskaya, T. P., Kushlinskii, D. N., Utkin, D. O., Loginov, V. I., Braga, E. A., Kushlinskii, N. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biomedical and Life Sciences Biomedicine Cancer Cancer therapies Carcinoma, Ovarian Epithelial - genetics Care and treatment Cell Biology Correlation analysis Development and progression DNA methylation DNA Methylation - genetics Female Gene Expression Regulation, Neoplastic - genetics Gene regulation Genes Genetic aspects Humans Internal Medicine Laboratory Medicine Medical research Metastases Metastasis Methylation MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Oncology Ovarian cancer Ovarian Neoplasms - pathology Pathology Tumors Womens health
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