Low-pH Molten Globule-Like Form of CIA17, a Chitooligosaccharide-Specific Lectin from the Phloem Exudate of Coccinia indica, Retains Carbohydrate-Binding Ability

pH-induced changes in the conformation, structural dynamics, and carbohydrate-binding activity of Coccinia indica agglutinin (CIA17), a PP2-type lectin, were investigated employing biophysical approaches. The secondary structure of CIA17 remains nearly unaltered over a wide pH range (2.0–8.5), while...

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Veröffentlicht in:	The journal of physical chemistry. B 2022-06, Vol.126 (22), p.4049-4060
Hauptverfasser:	Mondal, Saradamoni, Das, Somnath, Paul, Sumanta, Barik, Shilpa, Swamy, Musti J.
Format:	Artikel
Sprache:	eng
Schlagworte:	B: Biophysical and Biochemical Systems and Processes Chitin Chitosan Circular Dichroism Cucurbitaceae Exudates and Transudates Hydrogen-Ion Concentration Lectins Oligosaccharides Phloem - chemistry Protein Conformation Protein Denaturation Protein Folding Spectrometry, Fluorescence
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