Local Administration of Metformin Improves Bone Microarchitecture and Biomechanical Properties During Ruptured Canine Achilles Tendon–Calcaneus Interface Healing

Background: Tendon-bone interface (TBI) healing is a clinical dilemma that is closely relevant to new bone formation and remodeling at the repair site. Previous studies showed that metformin is an osteogenic inducer for stem cells in vitro and capable of stimulating bone regeneration in vivo. Hypoth...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The American journal of sports medicine 2022-07, Vol.50 (8), p.2145-2154
Hauptverfasser:	Shi, Qiang, Zhang, Tao, Chen, Yang, Xu, Yan, Deng, Zhenhan, Xu, Daqi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Gene expression Interfaces Sports medicine Stem cells Tendons
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!