MSX-122: Is an effective small molecule CXCR4 antagonist in cancer therapy?

•CXCL12/CXCR4 axis is involved in tumor cell proliferation, survival, and metastasis.•MSX-122 as a CXCR4 inhibitor can be effective in cancer therapy.•MSX-122 can increase the sensitivity of tumor cells to chemotherapy. Chemokines, a subgroup of cytokines along with their receptors, are involved in...

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Veröffentlicht in:	International immunopharmacology 2022-07, Vol.108, p.108863-108863, Article 108863
Hauptverfasser:	Ghasemi, Kimia, Ghasemi, Kosar
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Chemokine CXCR4 MSX-122
Online-Zugang:	Volltext
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