Hormone sensitive lipase ablation promotes bone regeneration

There is an inverse relationship between the differentiation of mesenchymal stem cells (MSCs) along either an adipocyte or osteoblast lineage, with lineage differentiation known to be mediated by transcription factors PPARγ and Runx2, respectively. Endogenous ligands for PPARγ are generated during t...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2022-09, Vol.1868 (9), p.166449-166449, Article 166449
Hauptverfasser:	Shen, Wen-Jun, Still II, Chris, Han, Lina, Yang, Pinglin, Chen, Jia, Wosczyna, Michael, Salmon, Benjamin Jean Rene, Perez, Kristy C., Li, Jingtao, Cuevas, Pedro L., Liu, Bo, Azhar, Salman, Helms, Jill, Qi, Lei S., Kraemer, Fredric B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone repair Hormone sensitive lipase Knockout mice
Online-Zugang:	Volltext
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