Excess fructose enhances oleatic cytotoxicity via reactive oxygen species production and causes necroptosis in hepatocytes

Non-alcoholic fatty liver disease (NAFLD), the hepatic phenotype of metabolic syndrome, has been identified as a major health concern as the number of cirrhosis and deaths associated with NAFLD is expected to increase. Although fructose intake has been considered to be a progressive factor in the pa...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2022-09, Vol.107, p.109052-109052, Article 109052
Hauptverfasser:	Kanazawa, Jo, Kakisaka, Keisuke, Suzuki, Yuji, Yonezawa, Takehiro, Abe, Hiroaki, Wang, Ting, Takikawa, Yasuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Fructose High-fat diet Lipotoxicity Necroptosis Non-alcoholic fatty liver disease
Online-Zugang:	Volltext
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