Population pharmacokinetics of polymyxin B and dosage strategy in critically ill patients with/without continuous renal replacement therapy

•Developing a population PK model of polymyxin B including patients receiving CRRT.•CRRT, CLCR and SOFA scores have effects on polymyxin B clearance.•References for polymyxin B dosage strategy in critically ill patients with/without CRRT. Polymyxin B is served as a last-line agent for Carbapenem-res...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2022-08, Vol.175, p.106214-106214, Article 106214
Hauptverfasser:	Luo, Xuemei, Zhang, Yusheng, Liang, Pei, Zhu, Huaijun, Li, Meijuan, Ding, Xuansheng, Zhang, Jinping
Format:	Artikel
Sprache:	eng
Schlagworte:	Continuous renal replacement therapy Critically ill patients Dosage strategy Polymyxin B Population pharmacokinetics
Online-Zugang:	Volltext
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