Histology-tailored multidisciplinary management of primary retroperitoneal sarcomas

Until recently, the recommendation for primary retroperitoneal sarcomas (RPS) was to perform a complete en-bloc gross excision, (neo) adjuvant treatments being options which were not validated by randomized studies, with a large discrepancy of use between centers. The heterogeneity of RPS, with thei...

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Veröffentlicht in:European journal of surgical oncology 2023-06, Vol.49 (6), p.1061-1067
Hauptverfasser: Bonvalot, S., Roland, C., Raut, C., Le Péchoux, C., Tzanis, D., Frezza, A.M., Gronchi, A.
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container_end_page 1067
container_issue 6
container_start_page 1061
container_title European journal of surgical oncology
container_volume 49
creator Bonvalot, S.
Roland, C.
Raut, C.
Le Péchoux, C.
Tzanis, D.
Frezza, A.M.
Gronchi, A.
description Until recently, the recommendation for primary retroperitoneal sarcomas (RPS) was to perform a complete en-bloc gross excision, (neo) adjuvant treatments being options which were not validated by randomized studies, with a large discrepancy of use between centers. The heterogeneity of RPS, with their different biological behaviour, renders a homogenous therapeutic and surgical approach probably inappropriate. Recent studies, both surgical and dedicated to adjuvant treatments, allow refining these recommendations. This review summarizes recent advances and directions.
doi_str_mv 10.1016/j.ejso.2022.05.010
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Chemotherapy
Diagnosis
Humans
leiomyosarcoma
Liposarcoma
Neoplasm Recurrence, Local - therapy
Radiotherapy
Retroperitoneal Neoplasms - surgery
Retroperitoneal sarcoma
Retroperitoneal tumour
Retrospective Studies
Sarcoma - surgery
Solitary fibrous Tumor
Surgery
Survival Rate
title Histology-tailored multidisciplinary management of primary retroperitoneal sarcomas
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