Characterization and determination of bovine immunoglobulin G subtypes in milk and dairy products by UPLC-MS

•Ultra-high performance liquid chromatography mass spectrometry was applied to detect IgG in milk.•Characteristic peptides were qualitatively confirmed by high-resolution mass spectrometry.•Isotope dimethylation can be the internal standard method to correct for matrix effects.•The validated method...

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Veröffentlicht in:	Food chemistry 2022-10, Vol.390, p.133170-133170, Article 133170
Hauptverfasser:	Zhang, Jingshun, Chen, Qin, Zhou, Ying, Zhang, Yunzhen, Ren, Yiping, Liu, Lianliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Characteristic peptides Enzymatic hydrolysis High-resolution mass spectrometry (HRMS) Immunoglobulin G Isotope dimethylation Ultra-high performance liquid chromatography (UPLC)
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