Lamprey immunity protein enables detection for bladder cancer through recognizing N-hydroxyacetylneuraminic acid (Neu5Gc)-modified as a diagnostic marker and exploration of its production mechanism

Previous studies have demonstrated that Neu5Gc is highly expressed in breast, ovarian, prostate, colon and lung cancers, but not in normal human cells. The presence of Neu5Gc is important for prognosis and is associated with aggressiveness, metastasis, and tumor grade. However, increased Neu5Gc in b...

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Veröffentlicht in:	Biochemical and biophysical research communications 2022-07, Vol.614, p.153-160
Hauptverfasser:	Cao, Xu, Yu, Song, Wang, Wei, Sun, Ruixiang, Wu, Zepan, Gao, Zhanfeng, Pang, Yue, Li, Qingwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Bladder cancer Glycosylation Glycosyltransferase LIP Neu5Gc
Online-Zugang:	Volltext
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