Incidence of adverse events with therapies targeting HER2-positive metastatic breast cancer: a literature review

Purpose Human epidermal growth factor receptor 2 (HER2)–targeted therapies improve survival for patients with HER2-positive breast cancer but carry risks of hematologic, cardiopulmonary, gastro-hepatobiliary, and other adverse events (AEs). In this review, we describe published AE incidences for HER...

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Veröffentlicht in:	Breast cancer research and treatment 2022-07, Vol.194 (1), p.1-11
Hauptverfasser:	Perez, Edith A., Dang, Chau, Lee, Caleb, Singh, Jasmeet, Wang, Kongming, Layton, J. Bradley, Gilsenan, Alicia, Hackshaw, Michelle D., Cortes, Javier
Format:	Artikel
Sprache:	eng
Schlagworte:	Ado-Trastuzumab Emtansine - adverse effects Analysis Antimitotic agents Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Biosimilar Pharmaceuticals - therapeutic use Breast cancer Breast Neoplasms - pathology Cancer Cancer research Care and treatment Complications and side effects Diarrhea Epidermal growth factor ErbB-2 protein Female Hepatotoxicity Humans Incidence Lapatinib - adverse effects Leukocytes Leukopenia Literature reviews Lung diseases Maytansine Medicine Medicine & Public Health Metastases Metastasis Nausea Neoplasms, Second Primary - etiology Oncology Oncology, Experimental Patients Pneumonitis Receptor, ErbB-2 - metabolism Review Trastuzumab Vomiting
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