Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study
To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence an...
Gespeichert in:
Veröffentlicht in: | Journal of viral hepatitis 2022-08, Vol.29 (8), p.596-603 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 603 |
---|---|
container_issue | 8 |
container_start_page | 596 |
container_title | Journal of viral hepatitis |
container_volume | 29 |
creator | Zhou, Guanlun Chen, Chao Han, Guorong Jiang, Hongxiu Cao, Minkai |
description | To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence and clinical outcomes between groups divided by HBV infection status. Spearman's correlation coefficient was used to evaluate the correlations among hepatitis B e antigen (HBeAg), HBV DNA and liver function. Logistic regression model was used to analyse the risk factors. In all, 1390 HBsAg‐positive pregnant women were enrolled. HBeAg titre and HBV DNA, ALT and AST were correlated (r = 0.743, p |
doi_str_mv | 10.1111/jvh.13700 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2666550604</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2687588260</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3530-7c819780b743230a089adf348a991266071f855145f46e934afc27dcdb66e2243</originalsourceid><addsrcrecordid>eNp1kc1u1DAUhS0EoqWw4AWQJTZlkdY_seOwayvKgCohIeg28jjXE48SJ9jJjObBeD_sTgEJCW9sH3_3XF0fhF5TckHTutzuugvKK0KeoFPKpSiYqvnTfBasIIKUJ-hFjFtCKGeCPkcnXAjFlGSn6OdX6PXsRh87N-E1zHsAj1tnLQTwM-5gSs-zi_ga71xYInbegskVOM56ToL2Ld5AviRR96lYJx-IeIC-d5mYAux0D94A1sPoN1nYeJ3s9-OQ2u3d3GHThdE7g1fX9397vMdXOMAcxjhlYQep6dIeXqJnVvcRXj3uZ-j77YdvN6vi7svHTzdXd4XhgpOiMorWlSLrquSME01UrVvLS6XrmjIpSUWtEoKWwpYSal5qa1jVmnYtJTBW8jN0fvSdwvhjSTM2g4smjaU9jEtskocUgkiS0bf_oNtxCek_MqUqoRSTJFHvjpRJI8UAtpmCG3Q4NJQ0OcsmZdk8ZJnYN4-Oy3qA9g_5O7wEXB6Bvevh8H-n5vP96mj5CyODq6k</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2687588260</pqid></control><display><type>article</type><title>Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Zhou, Guanlun ; Chen, Chao ; Han, Guorong ; Jiang, Hongxiu ; Cao, Minkai</creator><creatorcontrib>Zhou, Guanlun ; Chen, Chao ; Han, Guorong ; Jiang, Hongxiu ; Cao, Minkai</creatorcontrib><description>To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence and clinical outcomes between groups divided by HBV infection status. Spearman's correlation coefficient was used to evaluate the correlations among hepatitis B e antigen (HBeAg), HBV DNA and liver function. Logistic regression model was used to analyse the risk factors. In all, 1390 HBsAg‐positive pregnant women were enrolled. HBeAg titre and HBV DNA, ALT and AST were correlated (r = 0.743, p < 0.001; r = 0.813, p < 0.001). Overall GDM prevalence was 21%. GDM prevalence of HBV‐infected women with abnormal liver function was higher than those with normal liver function (26.8% vs. 20%, p = 0.027). Age over 35 years and abnormal liver function over 5 times ULN and 1–2 times ULN were independent risk factors for GDM prevalence with odds ratio (OR) of 1.858 (95% CI 1.227–2.815), 1.589 (95% CI 1.023–2.468) and 2.203 (95% CI 1.029–4.718), respectively. GDM prevalence in HBV‐infected pregnancies with abnormal liver function was higher than those with normal liver function. Age over 35 years and abnormal liver function were independent risk factors for GDM in HBV‐infected women.</description><identifier>ISSN: 1352-0504</identifier><identifier>EISSN: 1365-2893</identifier><identifier>DOI: 10.1111/jvh.13700</identifier><identifier>PMID: 35582862</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Chronic infection ; Deoxyribonucleic acid ; Diabetes mellitus ; DNA ; Gestational diabetes ; gestational diabetes mellitus ; Hepatitis B ; Hepatitis B e antigen ; hepatitis B e antigens ; Hepatitis B surface antigen ; hepatitis B virus ; Infections ; Liver ; liver function ; Pregnancy ; Risk factors ; viral load</subject><ispartof>Journal of viral hepatitis, 2022-08, Vol.29 (8), p.596-603</ispartof><rights>2022 John Wiley & Sons Ltd.</rights><rights>This article is protected by copyright. All rights reserved.</rights><rights>Copyright © 2022 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3530-7c819780b743230a089adf348a991266071f855145f46e934afc27dcdb66e2243</citedby><cites>FETCH-LOGICAL-c3530-7c819780b743230a089adf348a991266071f855145f46e934afc27dcdb66e2243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjvh.13700$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjvh.13700$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35582862$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhou, Guanlun</creatorcontrib><creatorcontrib>Chen, Chao</creatorcontrib><creatorcontrib>Han, Guorong</creatorcontrib><creatorcontrib>Jiang, Hongxiu</creatorcontrib><creatorcontrib>Cao, Minkai</creatorcontrib><title>Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study</title><title>Journal of viral hepatitis</title><addtitle>J Viral Hepat</addtitle><description>To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence and clinical outcomes between groups divided by HBV infection status. Spearman's correlation coefficient was used to evaluate the correlations among hepatitis B e antigen (HBeAg), HBV DNA and liver function. Logistic regression model was used to analyse the risk factors. In all, 1390 HBsAg‐positive pregnant women were enrolled. HBeAg titre and HBV DNA, ALT and AST were correlated (r = 0.743, p < 0.001; r = 0.813, p < 0.001). Overall GDM prevalence was 21%. GDM prevalence of HBV‐infected women with abnormal liver function was higher than those with normal liver function (26.8% vs. 20%, p = 0.027). Age over 35 years and abnormal liver function over 5 times ULN and 1–2 times ULN were independent risk factors for GDM prevalence with odds ratio (OR) of 1.858 (95% CI 1.227–2.815), 1.589 (95% CI 1.023–2.468) and 2.203 (95% CI 1.029–4.718), respectively. GDM prevalence in HBV‐infected pregnancies with abnormal liver function was higher than those with normal liver function. Age over 35 years and abnormal liver function were independent risk factors for GDM in HBV‐infected women.</description><subject>Chronic infection</subject><subject>Deoxyribonucleic acid</subject><subject>Diabetes mellitus</subject><subject>DNA</subject><subject>Gestational diabetes</subject><subject>gestational diabetes mellitus</subject><subject>Hepatitis B</subject><subject>Hepatitis B e antigen</subject><subject>hepatitis B e antigens</subject><subject>Hepatitis B surface antigen</subject><subject>hepatitis B virus</subject><subject>Infections</subject><subject>Liver</subject><subject>liver function</subject><subject>Pregnancy</subject><subject>Risk factors</subject><subject>viral load</subject><issn>1352-0504</issn><issn>1365-2893</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kc1u1DAUhS0EoqWw4AWQJTZlkdY_seOwayvKgCohIeg28jjXE48SJ9jJjObBeD_sTgEJCW9sH3_3XF0fhF5TckHTutzuugvKK0KeoFPKpSiYqvnTfBasIIKUJ-hFjFtCKGeCPkcnXAjFlGSn6OdX6PXsRh87N-E1zHsAj1tnLQTwM-5gSs-zi_ga71xYInbegskVOM56ToL2Ld5AviRR96lYJx-IeIC-d5mYAux0D94A1sPoN1nYeJ3s9-OQ2u3d3GHThdE7g1fX9397vMdXOMAcxjhlYQep6dIeXqJnVvcRXj3uZ-j77YdvN6vi7svHTzdXd4XhgpOiMorWlSLrquSME01UrVvLS6XrmjIpSUWtEoKWwpYSal5qa1jVmnYtJTBW8jN0fvSdwvhjSTM2g4smjaU9jEtskocUgkiS0bf_oNtxCek_MqUqoRSTJFHvjpRJI8UAtpmCG3Q4NJQ0OcsmZdk8ZJnYN4-Oy3qA9g_5O7wEXB6Bvevh8H-n5vP96mj5CyODq6k</recordid><startdate>202208</startdate><enddate>202208</enddate><creator>Zhou, Guanlun</creator><creator>Chen, Chao</creator><creator>Han, Guorong</creator><creator>Jiang, Hongxiu</creator><creator>Cao, Minkai</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>202208</creationdate><title>Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study</title><author>Zhou, Guanlun ; Chen, Chao ; Han, Guorong ; Jiang, Hongxiu ; Cao, Minkai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3530-7c819780b743230a089adf348a991266071f855145f46e934afc27dcdb66e2243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Chronic infection</topic><topic>Deoxyribonucleic acid</topic><topic>Diabetes mellitus</topic><topic>DNA</topic><topic>Gestational diabetes</topic><topic>gestational diabetes mellitus</topic><topic>Hepatitis B</topic><topic>Hepatitis B e antigen</topic><topic>hepatitis B e antigens</topic><topic>Hepatitis B surface antigen</topic><topic>hepatitis B virus</topic><topic>Infections</topic><topic>Liver</topic><topic>liver function</topic><topic>Pregnancy</topic><topic>Risk factors</topic><topic>viral load</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhou, Guanlun</creatorcontrib><creatorcontrib>Chen, Chao</creatorcontrib><creatorcontrib>Han, Guorong</creatorcontrib><creatorcontrib>Jiang, Hongxiu</creatorcontrib><creatorcontrib>Cao, Minkai</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of viral hepatitis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhou, Guanlun</au><au>Chen, Chao</au><au>Han, Guorong</au><au>Jiang, Hongxiu</au><au>Cao, Minkai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study</atitle><jtitle>Journal of viral hepatitis</jtitle><addtitle>J Viral Hepat</addtitle><date>2022-08</date><risdate>2022</risdate><volume>29</volume><issue>8</issue><spage>596</spage><epage>603</epage><pages>596-603</pages><issn>1352-0504</issn><eissn>1365-2893</eissn><abstract>To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence and clinical outcomes between groups divided by HBV infection status. Spearman's correlation coefficient was used to evaluate the correlations among hepatitis B e antigen (HBeAg), HBV DNA and liver function. Logistic regression model was used to analyse the risk factors. In all, 1390 HBsAg‐positive pregnant women were enrolled. HBeAg titre and HBV DNA, ALT and AST were correlated (r = 0.743, p < 0.001; r = 0.813, p < 0.001). Overall GDM prevalence was 21%. GDM prevalence of HBV‐infected women with abnormal liver function was higher than those with normal liver function (26.8% vs. 20%, p = 0.027). Age over 35 years and abnormal liver function over 5 times ULN and 1–2 times ULN were independent risk factors for GDM prevalence with odds ratio (OR) of 1.858 (95% CI 1.227–2.815), 1.589 (95% CI 1.023–2.468) and 2.203 (95% CI 1.029–4.718), respectively. GDM prevalence in HBV‐infected pregnancies with abnormal liver function was higher than those with normal liver function. Age over 35 years and abnormal liver function were independent risk factors for GDM in HBV‐infected women.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>35582862</pmid><doi>10.1111/jvh.13700</doi><tpages>8</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1352-0504 |
ispartof | Journal of viral hepatitis, 2022-08, Vol.29 (8), p.596-603 |
issn | 1352-0504 1365-2893 |
language | eng |
recordid | cdi_proquest_miscellaneous_2666550604 |
source | Wiley Online Library Journals Frontfile Complete |
subjects | Chronic infection Deoxyribonucleic acid Diabetes mellitus DNA Gestational diabetes gestational diabetes mellitus Hepatitis B Hepatitis B e antigen hepatitis B e antigens Hepatitis B surface antigen hepatitis B virus Infections Liver liver function Pregnancy Risk factors viral load |
title | Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T18%3A01%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relationship%20between%20different%20hepatitis%20B%20virus%20infection%20status%20and%20gestational%20diabetes%20mellitus%20prevalence%20among%20pregnant%20women%20with%20chronic%20HBV%20infection:%20A%20retrospective%20study&rft.jtitle=Journal%20of%20viral%20hepatitis&rft.au=Zhou,%20Guanlun&rft.date=2022-08&rft.volume=29&rft.issue=8&rft.spage=596&rft.epage=603&rft.pages=596-603&rft.issn=1352-0504&rft.eissn=1365-2893&rft_id=info:doi/10.1111/jvh.13700&rft_dat=%3Cproquest_cross%3E2687588260%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2687588260&rft_id=info:pmid/35582862&rfr_iscdi=true |