High mobility group protein B1 decreases surface localization of PD-1 to augment T-cell activation

High-mobility group protein B1 (HMGB1) is a danger signaling molecule that has been found to trigger an effective antitumor immune response. However, the mechanisms underlying its antitumor effects are not fully understood. Here, we found that HMGB1 release induced by chemotherapy in patients with n...

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Veröffentlicht in:Cancer immunology research 2022-07, Vol.10 (7), p.844-855
Hauptverfasser: Gao, Qun, Wang, Shumin, Li, Feng, Lian, Jingyao, Cheng, Shaoyan, Yue, Dongli, Zhang, Zhen, Liu, Shasha, Ren, Feifei, Zhang, Daiqun, Wang, Shengdian, Wang, Liping, Zhang, Yi
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Sprache:eng
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