Transesterification of Non‐Activated Esters Promoted by Small Molecules Mimicking the Active Site of Hydrolases

The synthesis of small molecules able to mimic the active site of hydrolytic enzymes has been largely pursued in recent decades. The high reaction rates and specificity shown by natural hydrolases present an attractive target, and yet the preparation of suitable small‐molecule mimics remains challen...

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Veröffentlicht in:	Angewandte Chemie International Edition 2022-08, Vol.61 (35), p.e202206072-n/a
Hauptverfasser:	Garrido‐González, José J., Sánchez‐Santos, Estela, Habib, Asmaa, Cuevas Ferreras, Ángel V., Sanz, Francisca, Morán, Joaquín R., Fuentes de Arriba, Ángel L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Artificial Hydrolase Chemical synthesis Chymotrypsin Enzyme Mimic Enzymes Esters Ethyl acetate Organocatalysis Oxyanion Hole Retirement Substrates Transesterification
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