Transcriptome Profiling Analysis Identifies LCP1 as a Contributor for Chidamide Resistance in Gastric Cancer

Background Gastric cancer (GC) remains a significant health problem and carries with it substantial morbidity and mortality. Chidamide is a novel and orally administered histone deacetylase (HDAC) inhibitor and has been demonstrated its anti-tumor efficacy on different kinds of hematological and sol...

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Veröffentlicht in:	Pharmaceutical research 2022-05, Vol.39 (5), p.867-876
Hauptverfasser:	Bao, Wenfang, Zhu, Zhe, Gao, Yong, Chen, Jingde
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antimitotic agents Antineoplastic agents Apoptosis Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Cancer Cell proliferation Cell survival Derepression Epigenetic inheritance Epigenetics Flow cytometry Gastric cancer Health aspects Histone deacetylase Lymphocytes Medical Law Morbidity Mortality Nucleotide sequence Oral administration Pharmacology/Toxicology Pharmacy Research Paper RNA Solid tumors Stomach cancer Transcriptomes Transcriptomics Xenografts
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