Tissue and circulating PD-L2: moving from health and immune-mediated diseases to head and neck oncology

Amongst the chief targets of immune-checkpoint inhibitors (ICIs), namely the Programmed cell death protein 1 (PD-1)/PD-Ligands (Ls) axis, most research has focused on PD-L1, while to date PD-L2 is still under-investigated. However, emerging data support PD-L2 relevant expression in malignancies of t...

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Veröffentlicht in:	Critical reviews in oncology/hematology 2022-07, Vol.175, p.103707-103707, Article 103707
Hauptverfasser:	Muraro, Elena, Romanò, Rebecca, Fanetti, Giuseppe, Vaccher, Emanuela, Turturici, Irene, Lupato, Valentina, La Torre, Fabio Biagio, Polesel, Jerry, Fratta, Elisabetta, Giacomarra, Vittorio, Franchin, Giovanni, Steffan, Agostino, Spina, Michele, Alfieri, Salvatore
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarker circulating head and neck cancer Immune-checkpoint inhibitors PD-1/PD-Ls axis PD-L2 predictive prognostic
Online-Zugang:	Volltext
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