Phillyrin attenuates norepinephrine-induced cardiac hypertrophy and inflammatory response by suppressing p38/ERK1/2 MAPK and AKT/NF-kappaB pathways

Phillyrin, a well-known natural compound from the dried fruits of Forsythia suspensa (Thunb.) Vahl., has shown anti-inflammatory, antioxidant and anti-virus activities as well as renal protective effects on diabetic nephropathy. In this study, we investigated whether phillyrin attenuated cardiac hyp...

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Veröffentlicht in:	European journal of pharmacology 2022-07, Vol.927, p.175022-175022, Article 175022
Hauptverfasser:	Tang, Kecheng, Zhong, Bin, Luo, Qingman, Liu, Qiao, Chen, Xin, Cao, Dayan, Li, Xiaohui, Yang, Shengqian
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac hypertrophy Inflammatory response NF-κB Norepinephrine p38 MAPK Phillyrin
Online-Zugang:	Volltext
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