Three-dimensional human leiomyoma xenografts induce angiogenesis by inducing hypoxia inducible factor-1 alpha

To characterize the method by which angiogenesis occurred in three-dimensional (3D) leiomyoma xenografts, and to assess the impact of hypoxia on two-dimensional (2D) and 3D myometrial and leiomyoma cells and leiomyoma xenografts in vivo. Laboratory study. Academic research. Cell cultures from patien...

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Veröffentlicht in:	F&S Science (Online) 2021-05, Vol.2 (2), p.219-227
Hauptverfasser:	Britten, Joy L., Malik, Minnie, Pekny, Carissa, DeAngelis, Anthony, Catherino, William H.
Format:	Artikel
Sprache:	eng
Schlagworte:	3D xenograft adrenomedullin Angiogenesis Animals Female Heterografts Humans Hypoxia leiomyoma Leiomyoma - metabolism Mice Neovascularization, Pathologic Oxygen Rats
Online-Zugang:	Volltext
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