Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is characterized by unexplained segmental hypertrophy that is usually most pronounced in the septum. While sarcomeric gene mutations are often the genetic basis for HCM, the mechanistic origin for the heterogeneous remodeling remains...

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Veröffentlicht in:	Cell reports (Cambridge) 2022-05, Vol.39 (6), p.110809-110809, Article 110809
Hauptverfasser:	Wehrens, Martijn, de Leeuw, Anne E, Wright-Clark, Maya, Eding, Joep E C, Boogerd, Cornelis J, Molenaar, Bas, van der Kraak, Petra H, Kuster, Diederik W D, van der Velden, Jolanda, Michels, Michelle, Vink, Aryan, van Rooij, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiomyopathy, Hypertrophic - genetics Heart Defects, Congenital Humans Hypertrophy Sarcomeres Transcriptome - genetics
Online-Zugang:	Volltext
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