SDH, a novel diarylheptane compound, is a potential treatment for inflammatory bowel disease by restoring epithelial barrier function

The global prevalence of inflammatory bowel disease (IBD) is increasing, and mucosal healing is the preferred treatment target of IBD. Sodium (aS,9 R)− 3-hydroxy-16,17-dimethoxy-15-oxidotricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexene-9-yl sulfate hydrate (SDH) is a novel diarylheptane com...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2022-07, Vol.151, p.113080-113080, Article 113080
Hauptverfasser:	Yang, Fei, Zhu, Xiaoqiang, Li, Liu, Wang, Yanping, Xie, Qing, Cao, Yu, Yu, Yunhui, Zhang, Minjie, Li, Dong, Li, Ling, Liu, Zhongtian, Zhang, Biyan, Chen, Zijun, Deng, Shiping, Li, Yunsen
Format:	Artikel
Sprache:	eng
Schlagworte:	Epithelial barrier function Inflammatory bowel disease Nonclinical toxicology Safety pharmacology Tight junction proteins
Online-Zugang:	Volltext
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