The Tmod cellular logic gate as a solution for tumor-selective immunotherapy

Immune cells that are engineered with receptors to integrate signals from multiple antigens offer a promising route to achieve the elusive property of therapeutic selectivity in cancer patients. Several types of multi-signal integrators have been described, among them mechanisms that pair activating...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2022-08, Vol.241, p.109030-109030, Article 109030
Hauptverfasser:	DiAndreth, Breanna, Hamburger, Agnes E., Xu, Han, Kamb, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	CAR-T LILRB1 LIR-1 Logic gate NOT gate Synthetic biology T cell therapy
Online-Zugang:	Volltext
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