Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis

There are sex differences in the pathophysiology of aortic valve (AV) calcification in patients with aortic stenosis, although the molecular and cellular mechanisms have not been elucidated. Aldosterone (Aldo) promotes proteoglycan synthesis in valve interstitial cells (VICs) from mitral valves via...

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Veröffentlicht in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2022-08, Vol.79 (8), p.1724-1737
Hauptverfasser: Matilla, Lara, Jover, Eva, Garaikoetxea, Mattie, Martín-Nuñez, Ernesto, Arrieta, Vanessa, García-Peña, Amaia, Navarro, Adela, Fernández-Celis, Amaya, Gainza, Alicia, Álvarez, Virginia, Álvarez de la Rosa, Diego, Sádaba, Rafael, Jaisser, Frederic, López-Andrés, Natalia
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Sprache:eng
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