Development of a glutaric acid production system equipped with stepwise feeding of monosodium glutamate by whole-cell bioconversion

In the bioproduction of glutaric acid, an emerging bioplastic monomer, α-ketoglutaric acid (α-KG) is required as an amine acceptor for 4-aminobutyrate aminotransferase (GabT)-driven conversion of 5-aminovalerate (5-AVA) to glutarate semialdehyde. Herein, instead of using expensive α-KG, an indirect...

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Veröffentlicht in:	Enzyme and microbial technology 2022-09, Vol.159, p.110053-110053, Article 110053
Hauptverfasser:	Cha, Haeng-Geun, Kim, Hee Taek, Park, See-Hyoung, Min, Kyoungseon, Kong, Youjung, Joo, Jeong Chan, Yang, Yung-Hun, Ahn, Jung-Oh, Lee, Jin-Suk, Park, Kyungmoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Glutaric acid Indirect α-ketoglutaric acid supplying system Monosodium glutamate (MSG) Stepwise feeding system α-ketoglutaric acid
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