Hyperkeratotic flexural erythema/granular parakeratosis responding to doxycycline

Hyperkeratotic flexural erythema (HKFE), also termed granular parakeratosis (GP), is a rare skin condition thought to be linked to a skin barrier dysfunction process, however the exact cause of this is yet to be determined. Management options are varied, with no consensus on treatment. Several previ...

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Veröffentlicht in:	Australasian journal of dermatology 2022-08, Vol.63 (3), p.368-371
Hauptverfasser:	Herat, Asoka, Gonzalez Matheus, Gabriela, Kumarasinghe, Sujit Prasad
Format:	Artikel
Sprache:	eng
Schlagworte:	Amoxicillin Clavulanic acid Doxycycline Erythema granular parakeratosis hyperkeratotic flexural erythema skin microbiome
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container_title	Australasian journal of dermatology
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creator	Herat, Asoka Gonzalez Matheus, Gabriela Kumarasinghe, Sujit Prasad
description	Hyperkeratotic flexural erythema (HKFE), also termed granular parakeratosis (GP), is a rare skin condition thought to be linked to a skin barrier dysfunction process, however the exact cause of this is yet to be determined. Management options are varied, with no consensus on treatment. Several previous reports have recorded successful treatment with amoxycillin‐clavulanic acid combination. We propose the use of oral doxycycline in addition to topical coconut oil compound as a treatment option in therapy resistant HKFE.
doi_str_mv	10.1111/ajd.13868
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subjects	Amoxicillin Clavulanic acid Doxycycline Erythema granular parakeratosis hyperkeratotic flexural erythema skin microbiome
title	Hyperkeratotic flexural erythema/granular parakeratosis responding to doxycycline
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