Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents

Selenium is an essential trace element that is crucial for cellular antioxidant defense against reactive oxygen species (ROS). Recently, many selenium-containing compounds have exhibited a wide spectrum of biological activities that make them promising scaffolds in Medicinal Chemistry, and, in parti...

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Veröffentlicht in:	Drug resistance updates 2022-07, Vol.63, p.100844-100844, Article 100844
Hauptverfasser:	Domínguez-Álvarez, Enrique, Rácz, Bálint, Marć, Małgorzata Anna, Nasim, Muhammad Jawad, Szemerédi, Nikoletta, Viktorová, Jitka, Jacob, Claus, Spengler, Gabriella
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy Cancer Drug combination Drug development Efflux pumps Free radicals Inflammation Multidrug resistance (MDR) Selenium Tellurium
Online-Zugang:	Volltext
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