Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality
Comorbid insomnia and poor sleep quality in Parkinson's disease (PD) are associated with a poor health-related quality of life (HRQoL). However, the relationship between HRQoL and sleep measures obtained using polysomnography (PSG) remains unclear. We aimed to examine the association between va...
Gespeichert in:
| Veröffentlicht in: | Parkinsonism & related disorders 2022-05, Vol.98, p.86-91 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 91 |
|---|---|
| container_issue | |
| container_start_page | 86 |
| container_title | Parkinsonism & related disorders |
| container_volume | 98 |
| creator | Tsuru, Ayumi Matsui, Kentaro Kimura, Ayano Yoshiike, Takuya Otsuki, Rei Nagao, Kentaro Hazumi, Megumi Utsumi, Tomohiro Fukumizu, Michio Mukai, Yohei Takahashi, Yuji Sakamoto, Takashi Kuriyama, Kenichi |
| description | Comorbid insomnia and poor sleep quality in Parkinson's disease (PD) are associated with a poor health-related quality of life (HRQoL). However, the relationship between HRQoL and sleep measures obtained using polysomnography (PSG) remains unclear. We aimed to examine the association between various sleep measures and HRQoL in PD patients.
We retrospectively included patients with PD who underwent PSG and responded to self-administered questionnaires including the Pittsburgh Sleep Quality Index (PSQI) and Medical Outcomes Study 36-Item Short-Form Health Survey.
The patients' (n = 120) mean age was 67.06 (SD = 8.77) years, and their mean Hoehn and Yahr stage was 2.25 (SD = 0.78). A higher PSQI score (worse subjective sleep quality) was correlated in PSG with shorter sleep latency, less N1 sleep, and more N2 sleep. Multiple regression analysis showed that the total PSQI score correlated with both physical and mental HRQoL (p |
| doi_str_mv | 10.1016/j.parkreldis.2022.04.014 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2661481976</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1353802022001109</els_id><sourcerecordid>2661481976</sourcerecordid><originalsourceid>FETCH-LOGICAL-c440t-b118697b313db5142fbfc0e11e68e3572189d8ac083019fa107a7ccf5b84dfb3</originalsourceid><addsrcrecordid>eNqFkctu1DAUhi0Eohd4BeQdbBKOb4nDrlRQkCqBRPeWL8eqh0wytZOivg8PiqczwLKrcxb_5dgfIZRBy4B17zftzuafGceQSsuB8xZkC0w-I6dM96JRjHfP6y6UaDRwOCFnpWwAoFcgXpIToRTv5KBOye8fI-KO1pxlzc5OHqmdAr1FOy63TW2wCwZ6t9oxLQ90jnRMEWma6Pd6QJrKPL0tezfagh_oBfUj2kz9nB-taZ6ow-UX4vRU5L61rG6Dfkn3SMvjWUfRK_Ii2rHg6-M8JzefP91cfmmuv119vby4bryUsDSOMd0NvRNMBKeY5NFFD8gYdhqF6jnTQ9DWgxbAhmgZ9Lb3PiqnZYhOnJN3h9hdnu9WLIvZpuJxHO2E81oM7zomNRv6rkr1QerzXErGaHY5bW1-MAzMHpHZmP-IzB6RAWkqomp9c2xZ3RbDP-NfJlXw8SDA-tT7hNkUn7CSCSnX3zFhTk-3_AGBgKtj</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2661481976</pqid></control><display><type>article</type><title>Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality</title><source>Elsevier ScienceDirect Journals</source><creator>Tsuru, Ayumi ; Matsui, Kentaro ; Kimura, Ayano ; Yoshiike, Takuya ; Otsuki, Rei ; Nagao, Kentaro ; Hazumi, Megumi ; Utsumi, Tomohiro ; Fukumizu, Michio ; Mukai, Yohei ; Takahashi, Yuji ; Sakamoto, Takashi ; Kuriyama, Kenichi</creator><creatorcontrib>Tsuru, Ayumi ; Matsui, Kentaro ; Kimura, Ayano ; Yoshiike, Takuya ; Otsuki, Rei ; Nagao, Kentaro ; Hazumi, Megumi ; Utsumi, Tomohiro ; Fukumizu, Michio ; Mukai, Yohei ; Takahashi, Yuji ; Sakamoto, Takashi ; Kuriyama, Kenichi</creatorcontrib><description>Comorbid insomnia and poor sleep quality in Parkinson's disease (PD) are associated with a poor health-related quality of life (HRQoL). However, the relationship between HRQoL and sleep measures obtained using polysomnography (PSG) remains unclear. We aimed to examine the association between various sleep measures and HRQoL in PD patients.
We retrospectively included patients with PD who underwent PSG and responded to self-administered questionnaires including the Pittsburgh Sleep Quality Index (PSQI) and Medical Outcomes Study 36-Item Short-Form Health Survey.
The patients' (n = 120) mean age was 67.06 (SD = 8.77) years, and their mean Hoehn and Yahr stage was 2.25 (SD = 0.78). A higher PSQI score (worse subjective sleep quality) was correlated in PSG with shorter sleep latency, less N1 sleep, and more N2 sleep. Multiple regression analysis showed that the total PSQI score correlated with both physical and mental HRQoL (p < 0.001 in both cases). However, neither type of HRQoL studied correlated with objective sleep measures, including indicators of sleep architecture, sleep-disordered breathing, and sleep related movement disorders.
Despite the association between subjective sleep quality and HRQoL, the associations between objective measures and HRQoL were negligible. Objective sleep fragmentation may not be perceived as a sleep disturbance in patients with PD, and therefore may not adversely affect their subjective health, given the paradoxical correlation between PSQI score and sleep architecture.
•Polysomnographic measures showed negligible correlation with HRQoL in PD patients.•Subjective sleep quality was associated with both mental and physical HRQoL.•Objective sleep fragmentation may not be well recognized in PD patients.</description><identifier>ISSN: 1353-8020</identifier><identifier>EISSN: 1873-5126</identifier><identifier>DOI: 10.1016/j.parkreldis.2022.04.014</identifier><identifier>PMID: 35526495</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Health-related quality of life ; Insomnia ; Non-motor symptoms ; Parkinson's disease ; Polysomnography ; Sleep disordered breathing</subject><ispartof>Parkinsonism & related disorders, 2022-05, Vol.98, p.86-91</ispartof><rights>2022 Elsevier Ltd</rights><rights>Copyright © 2022 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-b118697b313db5142fbfc0e11e68e3572189d8ac083019fa107a7ccf5b84dfb3</citedby><cites>FETCH-LOGICAL-c440t-b118697b313db5142fbfc0e11e68e3572189d8ac083019fa107a7ccf5b84dfb3</cites><orcidid>0000-0003-4538-5381</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1353802022001109$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35526495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsuru, Ayumi</creatorcontrib><creatorcontrib>Matsui, Kentaro</creatorcontrib><creatorcontrib>Kimura, Ayano</creatorcontrib><creatorcontrib>Yoshiike, Takuya</creatorcontrib><creatorcontrib>Otsuki, Rei</creatorcontrib><creatorcontrib>Nagao, Kentaro</creatorcontrib><creatorcontrib>Hazumi, Megumi</creatorcontrib><creatorcontrib>Utsumi, Tomohiro</creatorcontrib><creatorcontrib>Fukumizu, Michio</creatorcontrib><creatorcontrib>Mukai, Yohei</creatorcontrib><creatorcontrib>Takahashi, Yuji</creatorcontrib><creatorcontrib>Sakamoto, Takashi</creatorcontrib><creatorcontrib>Kuriyama, Kenichi</creatorcontrib><title>Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality</title><title>Parkinsonism & related disorders</title><addtitle>Parkinsonism Relat Disord</addtitle><description>Comorbid insomnia and poor sleep quality in Parkinson's disease (PD) are associated with a poor health-related quality of life (HRQoL). However, the relationship between HRQoL and sleep measures obtained using polysomnography (PSG) remains unclear. We aimed to examine the association between various sleep measures and HRQoL in PD patients.
We retrospectively included patients with PD who underwent PSG and responded to self-administered questionnaires including the Pittsburgh Sleep Quality Index (PSQI) and Medical Outcomes Study 36-Item Short-Form Health Survey.
The patients' (n = 120) mean age was 67.06 (SD = 8.77) years, and their mean Hoehn and Yahr stage was 2.25 (SD = 0.78). A higher PSQI score (worse subjective sleep quality) was correlated in PSG with shorter sleep latency, less N1 sleep, and more N2 sleep. Multiple regression analysis showed that the total PSQI score correlated with both physical and mental HRQoL (p < 0.001 in both cases). However, neither type of HRQoL studied correlated with objective sleep measures, including indicators of sleep architecture, sleep-disordered breathing, and sleep related movement disorders.
Despite the association between subjective sleep quality and HRQoL, the associations between objective measures and HRQoL were negligible. Objective sleep fragmentation may not be perceived as a sleep disturbance in patients with PD, and therefore may not adversely affect their subjective health, given the paradoxical correlation between PSQI score and sleep architecture.
•Polysomnographic measures showed negligible correlation with HRQoL in PD patients.•Subjective sleep quality was associated with both mental and physical HRQoL.•Objective sleep fragmentation may not be well recognized in PD patients.</description><subject>Health-related quality of life</subject><subject>Insomnia</subject><subject>Non-motor symptoms</subject><subject>Parkinson's disease</subject><subject>Polysomnography</subject><subject>Sleep disordered breathing</subject><issn>1353-8020</issn><issn>1873-5126</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqFkctu1DAUhi0Eohd4BeQdbBKOb4nDrlRQkCqBRPeWL8eqh0wytZOivg8PiqczwLKrcxb_5dgfIZRBy4B17zftzuafGceQSsuB8xZkC0w-I6dM96JRjHfP6y6UaDRwOCFnpWwAoFcgXpIToRTv5KBOye8fI-KO1pxlzc5OHqmdAr1FOy63TW2wCwZ6t9oxLQ90jnRMEWma6Pd6QJrKPL0tezfagh_oBfUj2kz9nB-taZ6ow-UX4vRU5L61rG6Dfkn3SMvjWUfRK_Ii2rHg6-M8JzefP91cfmmuv119vby4bryUsDSOMd0NvRNMBKeY5NFFD8gYdhqF6jnTQ9DWgxbAhmgZ9Lb3PiqnZYhOnJN3h9hdnu9WLIvZpuJxHO2E81oM7zomNRv6rkr1QerzXErGaHY5bW1-MAzMHpHZmP-IzB6RAWkqomp9c2xZ3RbDP-NfJlXw8SDA-tT7hNkUn7CSCSnX3zFhTk-3_AGBgKtj</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Tsuru, Ayumi</creator><creator>Matsui, Kentaro</creator><creator>Kimura, Ayano</creator><creator>Yoshiike, Takuya</creator><creator>Otsuki, Rei</creator><creator>Nagao, Kentaro</creator><creator>Hazumi, Megumi</creator><creator>Utsumi, Tomohiro</creator><creator>Fukumizu, Michio</creator><creator>Mukai, Yohei</creator><creator>Takahashi, Yuji</creator><creator>Sakamoto, Takashi</creator><creator>Kuriyama, Kenichi</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4538-5381</orcidid></search><sort><creationdate>20220501</creationdate><title>Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality</title><author>Tsuru, Ayumi ; Matsui, Kentaro ; Kimura, Ayano ; Yoshiike, Takuya ; Otsuki, Rei ; Nagao, Kentaro ; Hazumi, Megumi ; Utsumi, Tomohiro ; Fukumizu, Michio ; Mukai, Yohei ; Takahashi, Yuji ; Sakamoto, Takashi ; Kuriyama, Kenichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-b118697b313db5142fbfc0e11e68e3572189d8ac083019fa107a7ccf5b84dfb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Health-related quality of life</topic><topic>Insomnia</topic><topic>Non-motor symptoms</topic><topic>Parkinson's disease</topic><topic>Polysomnography</topic><topic>Sleep disordered breathing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsuru, Ayumi</creatorcontrib><creatorcontrib>Matsui, Kentaro</creatorcontrib><creatorcontrib>Kimura, Ayano</creatorcontrib><creatorcontrib>Yoshiike, Takuya</creatorcontrib><creatorcontrib>Otsuki, Rei</creatorcontrib><creatorcontrib>Nagao, Kentaro</creatorcontrib><creatorcontrib>Hazumi, Megumi</creatorcontrib><creatorcontrib>Utsumi, Tomohiro</creatorcontrib><creatorcontrib>Fukumizu, Michio</creatorcontrib><creatorcontrib>Mukai, Yohei</creatorcontrib><creatorcontrib>Takahashi, Yuji</creatorcontrib><creatorcontrib>Sakamoto, Takashi</creatorcontrib><creatorcontrib>Kuriyama, Kenichi</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Parkinsonism & related disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsuru, Ayumi</au><au>Matsui, Kentaro</au><au>Kimura, Ayano</au><au>Yoshiike, Takuya</au><au>Otsuki, Rei</au><au>Nagao, Kentaro</au><au>Hazumi, Megumi</au><au>Utsumi, Tomohiro</au><au>Fukumizu, Michio</au><au>Mukai, Yohei</au><au>Takahashi, Yuji</au><au>Sakamoto, Takashi</au><au>Kuriyama, Kenichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality</atitle><jtitle>Parkinsonism & related disorders</jtitle><addtitle>Parkinsonism Relat Disord</addtitle><date>2022-05-01</date><risdate>2022</risdate><volume>98</volume><spage>86</spage><epage>91</epage><pages>86-91</pages><issn>1353-8020</issn><eissn>1873-5126</eissn><abstract>Comorbid insomnia and poor sleep quality in Parkinson's disease (PD) are associated with a poor health-related quality of life (HRQoL). However, the relationship between HRQoL and sleep measures obtained using polysomnography (PSG) remains unclear. We aimed to examine the association between various sleep measures and HRQoL in PD patients.
We retrospectively included patients with PD who underwent PSG and responded to self-administered questionnaires including the Pittsburgh Sleep Quality Index (PSQI) and Medical Outcomes Study 36-Item Short-Form Health Survey.
The patients' (n = 120) mean age was 67.06 (SD = 8.77) years, and their mean Hoehn and Yahr stage was 2.25 (SD = 0.78). A higher PSQI score (worse subjective sleep quality) was correlated in PSG with shorter sleep latency, less N1 sleep, and more N2 sleep. Multiple regression analysis showed that the total PSQI score correlated with both physical and mental HRQoL (p < 0.001 in both cases). However, neither type of HRQoL studied correlated with objective sleep measures, including indicators of sleep architecture, sleep-disordered breathing, and sleep related movement disorders.
Despite the association between subjective sleep quality and HRQoL, the associations between objective measures and HRQoL were negligible. Objective sleep fragmentation may not be perceived as a sleep disturbance in patients with PD, and therefore may not adversely affect their subjective health, given the paradoxical correlation between PSQI score and sleep architecture.
•Polysomnographic measures showed negligible correlation with HRQoL in PD patients.•Subjective sleep quality was associated with both mental and physical HRQoL.•Objective sleep fragmentation may not be well recognized in PD patients.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>35526495</pmid><doi>10.1016/j.parkreldis.2022.04.014</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-4538-5381</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1353-8020 |
| ispartof | Parkinsonism & related disorders, 2022-05, Vol.98, p.86-91 |
| issn | 1353-8020 1873-5126 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2661481976 |
| source | Elsevier ScienceDirect Journals |
| subjects | Health-related quality of life Insomnia Non-motor symptoms Parkinson's disease Polysomnography Sleep disordered breathing |
| title | Sleep disturbance and health-related quality of life in Parkinson's disease: A clear correlation between health-related quality of life and subjective sleep quality |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T08%3A54%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sleep%20disturbance%20and%20health-related%20quality%20of%20life%20in%20Parkinson's%20disease:%20A%20clear%20correlation%20between%20health-related%20quality%20of%20life%20and%20subjective%20sleep%20quality&rft.jtitle=Parkinsonism%20&%20related%20disorders&rft.au=Tsuru,%20Ayumi&rft.date=2022-05-01&rft.volume=98&rft.spage=86&rft.epage=91&rft.pages=86-91&rft.issn=1353-8020&rft.eissn=1873-5126&rft_id=info:doi/10.1016/j.parkreldis.2022.04.014&rft_dat=%3Cproquest_cross%3E2661481976%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2661481976&rft_id=info:pmid/35526495&rft_els_id=S1353802022001109&rfr_iscdi=true |