A multivariate methodology for material sparing characterization and blend design in drug product development

[Display omitted] This study developed a material and time saving method for powder characterization. Building on an earlier developed raw material property database for use towards development of pharmaceutical dry powder processes, blends were selected in an efficient way to include maximal variab...

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Veröffentlicht in:	International journal of pharmaceutics 2022-06, Vol.621, p.121801-121801, Article 121801
Hauptverfasser:	Dhondt, Jens, Eeckhout, Yasmine, Bertels, Johny, Kumar, Ashish, Van Snick, Bernd, Klingeleers, Didier, Vervaet, Chris, De Beer, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Direct compression Material characterization Multivariate data analysis Pharmaceutical drug product development Principal component analysis
Online-Zugang:	Volltext
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