IL-10 inhibits osteoclast differentiation and osteolysis through MEG3/IRF8 pathway

Osteolysis caused by wear particles is the main reason for joint replacement failure. Inhibition of osteoclast differentiation relieves wear particle-induced osteolysis. Our study aimed to explore the effect of lncRNA maternally expressed gene 3 (MEG3) on osteoclast differentiation and wear particle...

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Veröffentlicht in:	Cellular signalling 2022-07, Vol.95, p.110353-110353, Article 110353
Hauptverfasser:	Gao, Xuren, Ge, Jian, Zhou, Wangchen, Xu, Lei, Geng, Deqin
Format:	Artikel
Sprache:	eng
Schlagworte:	IL-10 IRF8 lncRNA MEG3 Osteoclasts Osteolysis STAT1
Online-Zugang:	Volltext
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