Metabolic perturbations and health impact from exposure to a combination of multiple harmful Maillard reaction products on Sprague-Dawley rats

The present study aimed to investigate the metabolic perturbations and health impact of the co-accumulation of Maillard reaction products (MRPs), including acrylamide, harmane, and N -(carboxymethyl)lysine (CML), via serum biochemical and histopathological examinations as well as metabolomic analysi...

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Veröffentlicht in:	Food & function 2022-05, Vol.13 (1), p.5515-5527
Hauptverfasser:	Quan, Wei, Lin, Yong, Xue, Chaoyi, Cheng, Yong, Luo, Jie, Lou, Aihua, Zeng, Maomao, He, Zhiyong, Shen, Qingwu, Chen, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamide Antioxidants Biosynthesis Blood glucose Body weight Carboxymethyllysine Diabetes mellitus Fumaric acid Glucose metabolism Health problems Health risks Injuries Insulin Kidneys Lysine Maillard reaction Maillard reaction products Metabolism Metabolomics Oxidative stress Pancreas Perturbation Tricarboxylic acid cycle
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