Sirolimus therapy restores the PD-1+ICOS+Tfh:CD45RA-Foxp3high activated Tfr cell balance in primary Sjögren’s syndrome

Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands. The current study was performed to investigate the roles of follicular helper T (Tfh) and follicular regulatory T (Tfr) subsets in patients with pSS, and...

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Veröffentlicht in:	Molecular immunology 2022-07, Vol.147, p.90-100
Hauptverfasser:	Wang, Yanlin, Guo, Hui, Liang, Zhaojun, Feng, Min, Wu, Yanyao, Qin, Yan, Zhao, Xiangcong, Gao, Chong, Liu, Guangying, Luo, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Follicular helper T cell subsets Follicular regulatory T cell subsets Primary Sjögren’s syndrome Regulatory T cell subsets Sirolimus
Online-Zugang:	Volltext
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