Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study
Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) is associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure. During 4.65 years (107,726 person-years) of follow-up,...
Gespeichert in:
| Veröffentlicht in: | The Science of the total environment 2022-07, Vol.831, p.154872-154872, Article 154872 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 154872 |
|---|---|
| container_issue | |
| container_start_page | 154872 |
| container_title | The Science of the total environment |
| container_volume | 831 |
| creator | Zheng, Congyi Tang, Haosu Wang, Xin Chen, Zuo Zhang, Linfeng Kang, Yuting Yang, Ying Chen, Lu Zhou, Haoqi Cai, Jiayin Cao, Xue Huang, Gang Wang, Zengwu |
| description | Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) is associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure. During 4.65 years (107,726 person-years) of follow-up, 942 cases of CVD events incident were identified among 23,143 participants from the China Hypertension Survey (CHS). Grading diastolic dysfunction was based on Recommendations for the evaluation of left ventricular diastolic function by echocardiography (2009). The annual average PM2.5, PM10 and NO2 concentrations were obtained by the chemical data assimilation system. Cox proportional hazards models were employed to estimate hazard ratios (HRs) for CVD in relation to LVDD. At baseline, the participants' mean age was 56.7 years, 46.8% were male. Compared to normal group, the HR (95% CI) of LVDD was 1.27 (1.07–1.50) after adjusting for all covariates. When stratified by ambient air pollution, we found that in middle and worst third PM2.5 areas, increased CVD risk was associated with increasing LVDD grade, both P for trend |
| doi_str_mv | 10.1016/j.scitotenv.2022.154872 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2660999159</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0048969722019659</els_id><sourcerecordid>2646723631</sourcerecordid><originalsourceid>FETCH-LOGICAL-c383t-c9da8e099c664084c703a09eb517ca8d96e98b79de6fc3cea3372e5bde7566553</originalsourceid><addsrcrecordid>eNqNkc2OFCEUhYnROO3oKyhLN9VCUfy560z8Szpxo2tCwa1IpxpaoCrpZ_ClpadnZqts7k34zrlwD0LvKNlSQsWHw7a4UFOFuG570vdbygcl-2doQ5XUHSW9eI42hAyq00LLG_SqlANpRyr6Et0wzrjivd6gP3uYKl4h1hzcMtuMfbClpjk47M9lWqKrIUVso8fOZh_SassjWMAWwCG2dpogNxNsj2O4ryHjU5rn5V7tUvTh0pWPeIdPOZUTNN8V2s2vlCsudfHn1-jFZOcCbx7qLfr5-dOPu6_d_vuXb3e7feeYYrVz2lsFRGsnxEDU4CRhlmgYOZXOKq8FaDVK7UFMjjmwjMke-OhBciE4Z7fo_dW3PeT3AqWaYygO5tlGSEsxvRDNXVOu_wMdhOyZYLSh8oq69r2SYTKnHI42nw0l5hKaOZin0MwlNHMNrSnfPgxZxiP4J91jSg3YXQFoW1kD5IsRRAc-5LZH41P455C_Y5uw8Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2646723631</pqid></control><display><type>article</type><title>Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Zheng, Congyi ; Tang, Haosu ; Wang, Xin ; Chen, Zuo ; Zhang, Linfeng ; Kang, Yuting ; Yang, Ying ; Chen, Lu ; Zhou, Haoqi ; Cai, Jiayin ; Cao, Xue ; Huang, Gang ; Wang, Zengwu</creator><creatorcontrib>Zheng, Congyi ; Tang, Haosu ; Wang, Xin ; Chen, Zuo ; Zhang, Linfeng ; Kang, Yuting ; Yang, Ying ; Chen, Lu ; Zhou, Haoqi ; Cai, Jiayin ; Cao, Xue ; Huang, Gang ; Wang, Zengwu</creatorcontrib><description>Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) is associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure. During 4.65 years (107,726 person-years) of follow-up, 942 cases of CVD events incident were identified among 23,143 participants from the China Hypertension Survey (CHS). Grading diastolic dysfunction was based on Recommendations for the evaluation of left ventricular diastolic function by echocardiography (2009). The annual average PM2.5, PM10 and NO2 concentrations were obtained by the chemical data assimilation system. Cox proportional hazards models were employed to estimate hazard ratios (HRs) for CVD in relation to LVDD. At baseline, the participants' mean age was 56.7 years, 46.8% were male. Compared to normal group, the HR (95% CI) of LVDD was 1.27 (1.07–1.50) after adjusting for all covariates. When stratified by ambient air pollution, we found that in middle and worst third PM2.5 areas, increased CVD risk was associated with increasing LVDD grade, both P for trend <0.05; The HRs (95% CI) of the CVD incidence were 1.52 (0.68–3.44), 4.97 (1.76–14.03) and 4.07 (1.44–11.49) for severe LVDD in the best, middle and worst third PM2.5 areas, respectively. Similar results were also presented for PM10 and NO2. In conclusion, our study highlights a stronger detectable adverse association between LVDD with CVD in worse ambient air quality assessed by any of the three primary ambient air pollutants (PM2.5, PM10 and NO2). Our study calls for appropriate interventions to reduce air pollution, which may promote great benefits to public health potentially by providing protection against the adverse CVD events.
[Display omitted]
•Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure.•A stronger detectable adverse association between LVDD with CVD in worse ambient air quality.•For those with cardiac dysfunction, other modifiable risk factors control should be much stricter and adequate personal protective equipment of air pollution should be more necessary when they are exposure to a certain concentration of air pollutants.•Appropriate interventions to reduce air pollution may promote great benefits to public health potentially by providing protection against the adverse CVD events.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2022.154872</identifier><identifier>PMID: 35358529</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>air ; Air Pollutants - analysis ; Air Pollution ; air quality ; Cardiac function ; Cardiovascular disease ; Cardiovascular Diseases - chemically induced ; Cardiovascular Diseases - epidemiology ; China ; cohort studies ; echocardiography ; environment ; Environmental Exposure ; Female ; Humans ; hypertension ; Male ; males ; Middle Aged ; Nitrogen Dioxide - analysis ; Particulate Matter - analysis ; Population ; Prospective cohort study ; Prospective Studies ; public health ; risk</subject><ispartof>The Science of the total environment, 2022-07, Vol.831, p.154872-154872, Article 154872</ispartof><rights>2022 The Authors</rights><rights>Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c383t-c9da8e099c664084c703a09eb517ca8d96e98b79de6fc3cea3372e5bde7566553</citedby><cites>FETCH-LOGICAL-c383t-c9da8e099c664084c703a09eb517ca8d96e98b79de6fc3cea3372e5bde7566553</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0048969722019659$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35358529$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zheng, Congyi</creatorcontrib><creatorcontrib>Tang, Haosu</creatorcontrib><creatorcontrib>Wang, Xin</creatorcontrib><creatorcontrib>Chen, Zuo</creatorcontrib><creatorcontrib>Zhang, Linfeng</creatorcontrib><creatorcontrib>Kang, Yuting</creatorcontrib><creatorcontrib>Yang, Ying</creatorcontrib><creatorcontrib>Chen, Lu</creatorcontrib><creatorcontrib>Zhou, Haoqi</creatorcontrib><creatorcontrib>Cai, Jiayin</creatorcontrib><creatorcontrib>Cao, Xue</creatorcontrib><creatorcontrib>Huang, Gang</creatorcontrib><creatorcontrib>Wang, Zengwu</creatorcontrib><title>Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) is associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure. During 4.65 years (107,726 person-years) of follow-up, 942 cases of CVD events incident were identified among 23,143 participants from the China Hypertension Survey (CHS). Grading diastolic dysfunction was based on Recommendations for the evaluation of left ventricular diastolic function by echocardiography (2009). The annual average PM2.5, PM10 and NO2 concentrations were obtained by the chemical data assimilation system. Cox proportional hazards models were employed to estimate hazard ratios (HRs) for CVD in relation to LVDD. At baseline, the participants' mean age was 56.7 years, 46.8% were male. Compared to normal group, the HR (95% CI) of LVDD was 1.27 (1.07–1.50) after adjusting for all covariates. When stratified by ambient air pollution, we found that in middle and worst third PM2.5 areas, increased CVD risk was associated with increasing LVDD grade, both P for trend <0.05; The HRs (95% CI) of the CVD incidence were 1.52 (0.68–3.44), 4.97 (1.76–14.03) and 4.07 (1.44–11.49) for severe LVDD in the best, middle and worst third PM2.5 areas, respectively. Similar results were also presented for PM10 and NO2. In conclusion, our study highlights a stronger detectable adverse association between LVDD with CVD in worse ambient air quality assessed by any of the three primary ambient air pollutants (PM2.5, PM10 and NO2). Our study calls for appropriate interventions to reduce air pollution, which may promote great benefits to public health potentially by providing protection against the adverse CVD events.
[Display omitted]
•Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure.•A stronger detectable adverse association between LVDD with CVD in worse ambient air quality.•For those with cardiac dysfunction, other modifiable risk factors control should be much stricter and adequate personal protective equipment of air pollution should be more necessary when they are exposure to a certain concentration of air pollutants.•Appropriate interventions to reduce air pollution may promote great benefits to public health potentially by providing protection against the adverse CVD events.</description><subject>air</subject><subject>Air Pollutants - analysis</subject><subject>Air Pollution</subject><subject>air quality</subject><subject>Cardiac function</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - chemically induced</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>China</subject><subject>cohort studies</subject><subject>echocardiography</subject><subject>environment</subject><subject>Environmental Exposure</subject><subject>Female</subject><subject>Humans</subject><subject>hypertension</subject><subject>Male</subject><subject>males</subject><subject>Middle Aged</subject><subject>Nitrogen Dioxide - analysis</subject><subject>Particulate Matter - analysis</subject><subject>Population</subject><subject>Prospective cohort study</subject><subject>Prospective Studies</subject><subject>public health</subject><subject>risk</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc2OFCEUhYnROO3oKyhLN9VCUfy560z8Szpxo2tCwa1IpxpaoCrpZ_ClpadnZqts7k34zrlwD0LvKNlSQsWHw7a4UFOFuG570vdbygcl-2doQ5XUHSW9eI42hAyq00LLG_SqlANpRyr6Et0wzrjivd6gP3uYKl4h1hzcMtuMfbClpjk47M9lWqKrIUVso8fOZh_SassjWMAWwCG2dpogNxNsj2O4ryHjU5rn5V7tUvTh0pWPeIdPOZUTNN8V2s2vlCsudfHn1-jFZOcCbx7qLfr5-dOPu6_d_vuXb3e7feeYYrVz2lsFRGsnxEDU4CRhlmgYOZXOKq8FaDVK7UFMjjmwjMke-OhBciE4Z7fo_dW3PeT3AqWaYygO5tlGSEsxvRDNXVOu_wMdhOyZYLSh8oq69r2SYTKnHI42nw0l5hKaOZin0MwlNHMNrSnfPgxZxiP4J91jSg3YXQFoW1kD5IsRRAc-5LZH41P455C_Y5uw8Q</recordid><startdate>20220720</startdate><enddate>20220720</enddate><creator>Zheng, Congyi</creator><creator>Tang, Haosu</creator><creator>Wang, Xin</creator><creator>Chen, Zuo</creator><creator>Zhang, Linfeng</creator><creator>Kang, Yuting</creator><creator>Yang, Ying</creator><creator>Chen, Lu</creator><creator>Zhou, Haoqi</creator><creator>Cai, Jiayin</creator><creator>Cao, Xue</creator><creator>Huang, Gang</creator><creator>Wang, Zengwu</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope></search><sort><creationdate>20220720</creationdate><title>Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study</title><author>Zheng, Congyi ; Tang, Haosu ; Wang, Xin ; Chen, Zuo ; Zhang, Linfeng ; Kang, Yuting ; Yang, Ying ; Chen, Lu ; Zhou, Haoqi ; Cai, Jiayin ; Cao, Xue ; Huang, Gang ; Wang, Zengwu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c383t-c9da8e099c664084c703a09eb517ca8d96e98b79de6fc3cea3372e5bde7566553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>air</topic><topic>Air Pollutants - analysis</topic><topic>Air Pollution</topic><topic>air quality</topic><topic>Cardiac function</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - chemically induced</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>China</topic><topic>cohort studies</topic><topic>echocardiography</topic><topic>environment</topic><topic>Environmental Exposure</topic><topic>Female</topic><topic>Humans</topic><topic>hypertension</topic><topic>Male</topic><topic>males</topic><topic>Middle Aged</topic><topic>Nitrogen Dioxide - analysis</topic><topic>Particulate Matter - analysis</topic><topic>Population</topic><topic>Prospective cohort study</topic><topic>Prospective Studies</topic><topic>public health</topic><topic>risk</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zheng, Congyi</creatorcontrib><creatorcontrib>Tang, Haosu</creatorcontrib><creatorcontrib>Wang, Xin</creatorcontrib><creatorcontrib>Chen, Zuo</creatorcontrib><creatorcontrib>Zhang, Linfeng</creatorcontrib><creatorcontrib>Kang, Yuting</creatorcontrib><creatorcontrib>Yang, Ying</creatorcontrib><creatorcontrib>Chen, Lu</creatorcontrib><creatorcontrib>Zhou, Haoqi</creatorcontrib><creatorcontrib>Cai, Jiayin</creatorcontrib><creatorcontrib>Cao, Xue</creatorcontrib><creatorcontrib>Huang, Gang</creatorcontrib><creatorcontrib>Wang, Zengwu</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zheng, Congyi</au><au>Tang, Haosu</au><au>Wang, Xin</au><au>Chen, Zuo</au><au>Zhang, Linfeng</au><au>Kang, Yuting</au><au>Yang, Ying</au><au>Chen, Lu</au><au>Zhou, Haoqi</au><au>Cai, Jiayin</au><au>Cao, Xue</au><au>Huang, Gang</au><au>Wang, Zengwu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>2022-07-20</date><risdate>2022</risdate><volume>831</volume><spage>154872</spage><epage>154872</epage><pages>154872-154872</pages><artnum>154872</artnum><issn>0048-9697</issn><eissn>1879-1026</eissn><abstract>Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) is associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure. During 4.65 years (107,726 person-years) of follow-up, 942 cases of CVD events incident were identified among 23,143 participants from the China Hypertension Survey (CHS). Grading diastolic dysfunction was based on Recommendations for the evaluation of left ventricular diastolic function by echocardiography (2009). The annual average PM2.5, PM10 and NO2 concentrations were obtained by the chemical data assimilation system. Cox proportional hazards models were employed to estimate hazard ratios (HRs) for CVD in relation to LVDD. At baseline, the participants' mean age was 56.7 years, 46.8% were male. Compared to normal group, the HR (95% CI) of LVDD was 1.27 (1.07–1.50) after adjusting for all covariates. When stratified by ambient air pollution, we found that in middle and worst third PM2.5 areas, increased CVD risk was associated with increasing LVDD grade, both P for trend <0.05; The HRs (95% CI) of the CVD incidence were 1.52 (0.68–3.44), 4.97 (1.76–14.03) and 4.07 (1.44–11.49) for severe LVDD in the best, middle and worst third PM2.5 areas, respectively. Similar results were also presented for PM10 and NO2. In conclusion, our study highlights a stronger detectable adverse association between LVDD with CVD in worse ambient air quality assessed by any of the three primary ambient air pollutants (PM2.5, PM10 and NO2). Our study calls for appropriate interventions to reduce air pollution, which may promote great benefits to public health potentially by providing protection against the adverse CVD events.
[Display omitted]
•Although previous studies indicated that the left ventricular diastolic dysfunction (LVDD) associated with cardiovascular disease (CVD), it remains unclear whether effects would be enhanced or accelerated by long-term air pollution exposure.•A stronger detectable adverse association between LVDD with CVD in worse ambient air quality.•For those with cardiac dysfunction, other modifiable risk factors control should be much stricter and adequate personal protective equipment of air pollution should be more necessary when they are exposure to a certain concentration of air pollutants.•Appropriate interventions to reduce air pollution may promote great benefits to public health potentially by providing protection against the adverse CVD events.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>35358529</pmid><doi>10.1016/j.scitotenv.2022.154872</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0048-9697 |
| ispartof | The Science of the total environment, 2022-07, Vol.831, p.154872-154872, Article 154872 |
| issn | 0048-9697 1879-1026 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2660999159 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | air Air Pollutants - analysis Air Pollution air quality Cardiac function Cardiovascular disease Cardiovascular Diseases - chemically induced Cardiovascular Diseases - epidemiology China cohort studies echocardiography environment Environmental Exposure Female Humans hypertension Male males Middle Aged Nitrogen Dioxide - analysis Particulate Matter - analysis Population Prospective cohort study Prospective Studies public health risk |
| title | Left ventricular diastolic dysfunction and cardiovascular disease in different ambient air pollution conditions: A prospective cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T03%3A05%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Left%20ventricular%20diastolic%20dysfunction%20and%20cardiovascular%20disease%20in%20different%20ambient%20air%20pollution%20conditions:%20A%20prospective%20cohort%20study&rft.jtitle=The%20Science%20of%20the%20total%20environment&rft.au=Zheng,%20Congyi&rft.date=2022-07-20&rft.volume=831&rft.spage=154872&rft.epage=154872&rft.pages=154872-154872&rft.artnum=154872&rft.issn=0048-9697&rft.eissn=1879-1026&rft_id=info:doi/10.1016/j.scitotenv.2022.154872&rft_dat=%3Cproquest_cross%3E2646723631%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2646723631&rft_id=info:pmid/35358529&rft_els_id=S0048969722019659&rfr_iscdi=true |