Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature

Objective To evaluate impact of a quality improvement (QI) outreach education on incidence of acute brain injury in transported premature neonates. Study design Neonates born at

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Veröffentlicht in:Journal of perinatology 2022-10, Vol.42 (10), p.1368-1373
Hauptverfasser: Mohammad, Khorshid, Momin, Sarfaraz, Murthy, Prashanth, Zein, Hussein, Scott, James N., Mehrem, Ayman Abou, Ghosh, Anirban, Javadyan, Artem, Awad, Essa Al, Venkata, Sujith Kumar Reddy Gurram, Paul, Renee, Rombough, Bryan, Bolderheij, Leah, Dossani, Salma, Montpetit, John, Eshemokhai, Peace, Fiedrich, Elsa, Thomas, Sumesh
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container_end_page 1373
container_issue 10
container_start_page 1368
container_title Journal of perinatology
container_volume 42
creator Mohammad, Khorshid
Momin, Sarfaraz
Murthy, Prashanth
Zein, Hussein
Scott, James N.
Mehrem, Ayman Abou
Ghosh, Anirban
Javadyan, Artem
Awad, Essa Al
Venkata, Sujith Kumar Reddy Gurram
Paul, Renee
Rombough, Bryan
Bolderheij, Leah
Dossani, Salma
Montpetit, John
Eshemokhai, Peace
Fiedrich, Elsa
Thomas, Sumesh
description Objective To evaluate impact of a quality improvement (QI) outreach education on incidence of acute brain injury in transported premature neonates. Study design Neonates born at
doi_str_mv 10.1038/s41372-022-01409-2
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Study design Neonates born at &lt;33 weeks gestation outside the tertiary center were included. The QI intervention was a combination of neuroprotection care bundle, in-person visits, and communication system improvement. Descriptive and regression (adjusting for Gestational Age, Birth Weight, Gender, and antenatal steroids, Mode of delivery, Apgars at 5 minutes, Prophylactic indomethacin, PDA, and Inotropes use) analyses were performed. The primary outcome was a composite of death and/or severe brain injury on cranial ultrasound using a validated classification. Results 181 neonates studied (93 before and 88 after). The rate and adjusted odds of death and/or severe brain injury reduced significantly post intervention (30% vs 15%) and (AOR 0.36, 95%CI, 0.15–0.85, P  = 0.02) respectively. Conclusion Implementation of outreach education targeting neuroprotection can reduce acute brain injury in transported premature neonates.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-022-01409-2</identifier><identifier>PMID: 35508716</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/308/409 ; 692/700/1421 ; 692/700/1538 ; Aircraft ; Birth rate ; Birth weight ; Brain ; Brain injury ; Communications systems ; Critical care ; Education ; Gestational age ; Head injuries ; Indomethacin ; Injury prevention ; Intervention ; Medical referrals ; Medicine ; Medicine &amp; Public Health ; Neonates ; Neuroprotection ; Newborn babies ; Nurses ; Pediatric Surgery ; Pediatrics ; Pregnancy complications ; Premature babies ; Quality control ; Quality improvement ; Risk factors ; Steroid hormones ; Steroids ; Traumatic brain injury ; Ultrasonic imaging</subject><ispartof>Journal of perinatology, 2022-10, Vol.42 (10), p.1368-1373</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2022</rights><rights>2022. 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Study design Neonates born at &lt;33 weeks gestation outside the tertiary center were included. The QI intervention was a combination of neuroprotection care bundle, in-person visits, and communication system improvement. Descriptive and regression (adjusting for Gestational Age, Birth Weight, Gender, and antenatal steroids, Mode of delivery, Apgars at 5 minutes, Prophylactic indomethacin, PDA, and Inotropes use) analyses were performed. The primary outcome was a composite of death and/or severe brain injury on cranial ultrasound using a validated classification. Results 181 neonates studied (93 before and 88 after). The rate and adjusted odds of death and/or severe brain injury reduced significantly post intervention (30% vs 15%) and (AOR 0.36, 95%CI, 0.15–0.85, P  = 0.02) respectively. 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Study design Neonates born at &lt;33 weeks gestation outside the tertiary center were included. The QI intervention was a combination of neuroprotection care bundle, in-person visits, and communication system improvement. Descriptive and regression (adjusting for Gestational Age, Birth Weight, Gender, and antenatal steroids, Mode of delivery, Apgars at 5 minutes, Prophylactic indomethacin, PDA, and Inotropes use) analyses were performed. The primary outcome was a composite of death and/or severe brain injury on cranial ultrasound using a validated classification. Results 181 neonates studied (93 before and 88 after). The rate and adjusted odds of death and/or severe brain injury reduced significantly post intervention (30% vs 15%) and (AOR 0.36, 95%CI, 0.15–0.85, P  = 0.02) respectively. Conclusion Implementation of outreach education targeting neuroprotection can reduce acute brain injury in transported premature neonates.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>35508716</pmid><doi>10.1038/s41372-022-01409-2</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-3568-7282</orcidid><orcidid>https://orcid.org/0000-0001-6580-0824</orcidid><orcidid>https://orcid.org/0000-0002-9598-3438</orcidid><orcidid>https://orcid.org/0000-0003-3805-949X</orcidid></addata></record>
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subjects 692/308/409
692/700/1421
692/700/1538
Aircraft
Birth rate
Birth weight
Brain
Brain injury
Communications systems
Critical care
Education
Gestational age
Head injuries
Indomethacin
Injury prevention
Intervention
Medical referrals
Medicine
Medicine & Public Health
Neonates
Neuroprotection
Newborn babies
Nurses
Pediatric Surgery
Pediatrics
Pregnancy complications
Premature babies
Quality control
Quality improvement
Risk factors
Steroid hormones
Steroids
Traumatic brain injury
Ultrasonic imaging
title Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature
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