Interaction between MHC diversity and constitution, gut microbiota and Astrovirus infections in a neotropical bat

Astroviruses (AstVs) infect numerous mammalian species including reservoirs such as bats. Peptides encoded by the genes of the highly polymorphic Major Histocompatibility Complex (MHC) form the first line of host defence against pathogens. Aside from direct involvement in mounting adaptive immune re...

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Veröffentlicht in:	Molecular ecology 2022-06, Vol.31 (12), p.3342-3359
Hauptverfasser:	Fleischer, Ramona, Schmid, Dominik W., Wasimuddin, Brändel, Stefan D., Rasche, Andrea, Corman, Victor M., Drosten, Christian, Tschapka, Marco, Sommer, Simone
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal populations Animals Artibeus jamaicensis astrovirus infection Bacteria Chiroptera Chiroptera - genetics Gastrointestinal Microbiome - genetics Genes Genetic diversity Genetics gut microbiome Immune response immunity Infections Intestinal microflora Major histocompatibility complex Major Histocompatibility Complex (MHC) Major Histocompatibility Complex - genetics Microbial activity Microbiota Microorganisms Pathogens Peptides zoonosis
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